Description : Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; with Grx3p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; mutant has increased aneuploidy tolerance; transcription regulated by Yap5p; GRX4 has a paralog, GRX3, that arose from the whole genome duplication [Source:SGD;Acc:S000000976]
Gene families : OG_03_0001408 (OF) Phylogenetic Tree(s): OG0001408_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YER174C | |
Cluster | HCCA: Cluster_7 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0009055 | electron transfer activity | IEA | Interproscan |
MF | GO:0015035 | protein disulfide oxidoreductase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |