YER174C


Description : Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; with Grx3p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; mutant has increased aneuploidy tolerance; transcription regulated by Yap5p; GRX4 has a paralog, GRX3, that arose from the whole genome duplication [Source:SGD;Acc:S000000976]


Gene families : OG_03_0001408 (OF) Phylogenetic Tree(s): OG0001408_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YER174C
Cluster HCCA: Cluster_7


Type GO Term Name Evidence Source
MF GO:0009055 electron transfer activity IEA Interproscan
MF GO:0015035 protein disulfide oxidoreductase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR002109 Glutaredoxin 158 221
IPR013766 Thioredoxin_domain 8 100
No external refs found!