Description : Integral ER membrane protein, regulates phospholipid metabolism; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PI4P levels by controlling access of Sac1p phosphatase to substrate PI4P in the PM; interacts with FFAT motifs in Opi1p, Swh1p, Osh2p, and Osh3p; involved in telomeric silencing; VAP homolog; SCS2 has a paralog, SCS22, that arose from the whole genome duplication [Source:SGD;Acc:S000000922]
Gene families : OG_03_0001272 (OF) Phylogenetic Tree(s): OG0001272_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YER120W | |
Cluster | HCCA: Cluster_50 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CAG80626 | No alias | Major sperm protein (MSP) domain | 0.02 | OF | |
KHC73547 | No alias | hypothetical protein;MSP (Major sperm protein) domain | 0.03 | OF | |
SPBC16G5.05c.1 | No alias | VAP family protein Scs2 [Source:PomBase;Acc:SPBC16G5.05c] | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000535 | MSP_dom | 4 | 107 |
No external refs found! |