Description : Fe(II)/2-oxoglutarate-dependent dioxygenase family member; catalyzes the repair of methyl-base lesions in both ss and dsDNA by oxidative demethylation; Poly(rA)-binding protein involved in mRNA poly(A) tail length and mRNA stability; role in translation termination efficiency; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; similar to human prolyl 4-hydroxylase OGFOD1; binds Fe(II) and 2-oxoglutarate [Source:SGD;Acc:S000000851]
Gene families : OG_03_0002109 (OF) Phylogenetic Tree(s): OG0002109_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YER049W | |
Cluster | HCCA: Cluster_69 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
POW03351 | No alias | Oxoglutarate/iron-dependent oxygenase, C-terminal... | 0.04 | OF | |
SPBC6B1.08c.1 | No alias | 2-oxoglutarate and Fe(II) dioxygenase domain containing... | 0.1 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005506 | iron ion binding | IEA | Interproscan |
MF | GO:0016706 | 2-oxoglutarate-dependent dioxygenase activity | IEA | Interproscan |
MF | GO:0031418 | L-ascorbic acid binding | IEA | Interproscan |
BP | GO:0055114 | oxidation-reduction process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |