Description : Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis; exclusive to eukaryotes, implicated as eukaryotic supplement to the bacterium-derived Fe-S cluster (ISC) assembly apparatus; involved in regulation of iron metabolism; member of the LYR protein family [Source:SGD;Acc:S000007237]

Gene families : OG_03_0002946 (OF) Phylogenetic Tree(s): OG0002946_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YER048W-A
Cluster HCCA: Cluster_15

Target Alias Description ECC score Gene Family Method Actions
EAU84000 No alias Complex 1 LYR protein 0.03 OF
EDO01839 No alias Complex 1 LYR protein 0.01 OF
EJF56471 No alias Complex 1 protein (LYR family) 0.03 OF
KHC76659 No alias hypothetical protein;Complex 1 protein (LYR family) 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR008011 Complex1_LYR 10 66
No external refs found!