Description : Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis; exclusive to eukaryotes, implicated as eukaryotic supplement to the bacterium-derived Fe-S cluster (ISC) assembly apparatus; involved in regulation of iron metabolism; member of the LYR protein family [Source:SGD;Acc:S000007237]
Gene families : OG_03_0002946 (OF) Phylogenetic Tree(s): OG0002946_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YER048W-A | |
Cluster | HCCA: Cluster_15 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
EAU84000 | No alias | Complex 1 LYR protein | 0.03 | OF | |
EDO01839 | No alias | Complex 1 LYR protein | 0.01 | OF | |
EJF56471 | No alias | Complex 1 protein (LYR family) | 0.03 | OF | |
KHC76659 | No alias | hypothetical protein;Complex 1 protein (LYR family) | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR008011 | Complex1_LYR | 10 | 66 |
No external refs found! |