YEL019C


Description : Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex; required for anchoring dsDNA breaks to the nuclear periphery; SMC5-SMC6 plays a key role in removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; required for efficient sister chromatid cohesion; mutants are sensitive to MMS, show increased spontaneous mutation and mitotic recombination; SUMOylates and inhibits Snf1p function; supports nucleolar function [Source:SGD;Acc:S000000745]


Gene families : OG_03_0001127 (OF) Phylogenetic Tree(s): OG0001127_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YEL019C

Target Alias Description ECC score Gene Family Method Actions
KHC79171 No alias hypothetical protein;Zinc-finger of the MIZ type in Nse subunit 0.02 OF

Type GO Term Name Evidence Source
MF GO:0008270 zinc ion binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR004181 Znf_MIZ 171 227
No external refs found!