Description : Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability [Source:SGD;Acc:S000002798]

Gene families : OG_03_0001537 (OF) Phylogenetic Tree(s): OG0001537_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR390C
Cluster HCCA: Cluster_66

Target Alias Description ECC score Gene Family Method Actions
AFR96216 No alias ubiquitin-like 1-activating enzyme E1 B;ThiF... 0.02 OF
ESU12073 No alias Ubiquitin-activating enzyme, catalytic cysteine domain 0.02 OF
KHC83553 No alias ubiquitin-like 1-activating enzyme E1... 0.05 OF
MGG_06733T0 No alias SUMO-activating enzyme subunit uba-2... 0.03 OF
SPBC16H5.03c.1 No alias SUMO activating enzyme E1-type Uba2 (predicted)... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR019572 UBA_E1_Cys 279 363
IPR000594 ThiF_NAD_FAD-bd 9 437
No external refs found!