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  5. YDR368W

YDR368W


Description : NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant [Source:SGD;Acc:S000002776]


Gene families : OG_03_0000063 (OF) Phylogenetic Tree(s): OG0000063_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YDR368W
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AFR93483 No alias oxidoreductase;Aldo/keto reductase family 0.03 OF
AFR98092 No alias alcohol dehydrogenase (NADP );Aldo/keto reductase family 0.06 OF
CAG81930 No alias NADP-dependent oxidoreductase domain 0.04 OF
CAG82106 No alias NADP-dependent oxidoreductase domain 0.03 OF
CAK39066 No alias Aldo/keto reductase family 0.02 OF
CAK39854 No alias Aldo/keto reductase family 0.02 OF
CAK96434 No alias Aldo/keto reductase family 0.02 OF
EAL90322 No alias glycerol dehydrogenase Gcy1, putative 0.03 OF
EED81456 No alias NADP-dependent oxidoreductase domain 0.03 OF
EJF59293 No alias Aldo/keto reductase family 0.04 OF
KHC81842 No alias D-arabinose 1-dehydrogenase;Aldo/keto reductase family 0.04 OF
MGG_02921T0 No alias Putative uncharacterized protein... 0.03 OF
SPAC26F1.07.1 No alias glucose 1-dehydrogenase (NADP+) (predicted)... 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR023210 NADP_OxRdtase_dom 23 291
No external refs found!