Description : NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant [Source:SGD;Acc:S000002776]
Gene families : OG_03_0000063 (OF) Phylogenetic Tree(s): OG0000063_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR368W | |
Cluster | HCCA: Cluster_19 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR93483 | No alias | oxidoreductase;Aldo/keto reductase family | 0.03 | OF | |
AFR98092 | No alias | alcohol dehydrogenase (NADP );Aldo/keto reductase family | 0.06 | OF | |
CAG81930 | No alias | NADP-dependent oxidoreductase domain | 0.04 | OF | |
CAG82106 | No alias | NADP-dependent oxidoreductase domain | 0.03 | OF | |
CAK39066 | No alias | Aldo/keto reductase family | 0.02 | OF | |
CAK39854 | No alias | Aldo/keto reductase family | 0.02 | OF | |
CAK96434 | No alias | Aldo/keto reductase family | 0.02 | OF | |
EAL90322 | No alias | glycerol dehydrogenase Gcy1, putative | 0.03 | OF | |
EED81456 | No alias | NADP-dependent oxidoreductase domain | 0.03 | OF | |
EJF59293 | No alias | Aldo/keto reductase family | 0.04 | OF | |
KHC81842 | No alias | D-arabinose 1-dehydrogenase;Aldo/keto reductase family | 0.04 | OF | |
MGG_02921T0 | No alias | Putative uncharacterized protein... | 0.03 | OF | |
SPAC26F1.07.1 | No alias | glucose 1-dehydrogenase (NADP+) (predicted)... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR023210 | NADP_OxRdtase_dom | 23 | 291 |
No external refs found! |