POW15502

Description : MCM OB domain;MCM N-terminal domain;MCM domain;MCM, AAA-lid domain;DNA replication licensing factor Mcm2

Gene families : OG_03_0002205 (OF) Phylogenetic Tree(s): OG0002205_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: POW15502
Cluster	HCCA: Cluster_31

Target	Alias	Description	ECC score	Gene Family Method
AFR96561	No alias	minichromosome maintenance protein 2;MCM P-loop...	0.01	OF
CAK40318	No alias	MCM N-terminal domain	0.01	OF
EAL92185	No alias	DNA replication licensing factor Mcm2, putative	0.02	OF
EAU91392	No alias	DNA replication licensing factor cdc19	0.02	OF
EGR44530	No alias	MCM, AAA-lid domain	0.03	OF
MGG_08122T0	No alias	DNA replication licensing factor mcm2...	0.01	OF
YBL023C	No alias	Protein involved in DNA replication; component of the...	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006270	DNA replication initiation	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010639	negative regulation of organelle organization	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0032780	negative regulation of ATPase activity	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033043	regulation of organelle organization	None	Extended
BP	GO:0033044	regulation of chromosome organization	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
CC	GO:0042555	MCM complex	IEA	Interproscan
BP	GO:0043086	negative regulation of catalytic activity	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043462	regulation of ATPase activity	None	Extended
BP	GO:0044092	negative regulation of molecular function	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050790	regulation of catalytic activity	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051095	regulation of helicase activity	None	Extended
BP	GO:0051097	negative regulation of helicase activity	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051129	negative regulation of cellular component organization	None	Extended
BP	GO:0051336	regulation of hydrolase activity	None	Extended
BP	GO:0051346	negative regulation of hydrolase activity	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065009	regulation of molecular function	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1905462	regulation of DNA duplex unwinding	None	Extended
BP	GO:1905463	negative regulation of DNA duplex unwinding	None	Extended
BP	GO:1905774	regulation of DNA helicase activity	None	Extended
BP	GO:1905775	negative regulation of DNA helicase activity	IEA	Interproscan
BP	GO:2001251	negative regulation of chromosome organization	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR033762	MCM_OB	307	433
IPR027925	MCM_N	209	298
IPR001208	MCM_dom	474	696
IPR041562	MCM_lid	725	807
IPR008045	MCM2	53	194

External Links

No external refs found!

POW15502

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation