Description : Cu(+2)-transporting P-type ATPase; required for export of copper from the cytosol into an extracytosolic compartment; similar to human proteins involved in Menkes and Wilsons diseases; protein abundance increases in response to DNA replication stress; affects TBSV model (+)RNA virus replication by regulating copper metabolism; human homologs ATP7A and ATP7B both complement yeast null mutant [Source:SGD;Acc:S000002678]
Gene families : OG_03_0001499 (OF) Phylogenetic Tree(s): OG0001499_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR270W | |
Cluster | HCCA: Cluster_53 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA67808 | No alias | E1-E2 ATPase | 0.03 | OF | |
CAK43903 | No alias | E1-E2 ATPase | 0.01 | OF | |
KHC75200 | No alias | heavy metal translocating P-type ATPase;E1-E2... | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0030001 | metal ion transport | IEA | Interproscan |
MF | GO:0046872 | metal ion binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |