Description : 5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p [Source:SGD;Acc:S000002640]
Gene families : OG_03_0002997 (OF) Phylogenetic Tree(s): OG0002997_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR232W | |
Cluster | HCCA: Cluster_70 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
KHC70813 | No alias | 5-aminolevulinate synthase,... | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0009058 | biosynthetic process | IEA | Interproscan |
MF | GO:0030170 | pyridoxal phosphate binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR004839 | Aminotransferase_I/II | 114 | 480 |
No external refs found! |