Description : Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence; protein abundance increases in response to DNA replication stress; mutations affecting Adk1p catalytic activity deregulate expression of phosphate utilization genes PHO5 and PHO84; human homolog AK1 can complement yeast adk1 mutant [Source:SGD;Acc:S000002634]
Gene families : OG_03_0002828 (OF) Phylogenetic Tree(s): OG0002828_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR226W | |
Cluster | HCCA: Cluster_67 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR98203 | No alias | adenylate kinase 1;Adenylate kinase, active site lid | 0.02 | OF | |
EDN96680 | No alias | Adenylate kinase, active site lid domain | 0.02 | OF | |
ESU18050 | No alias | adenylate kinase cytosolic | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004017 | adenylate kinase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR007862 | Adenylate_kinase_lid-dom | 134 | 169 |
No external refs found! |