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  5. YDR180W

YDR180W


Description : Subunit of cohesin loading factor (Scc2p-Scc4p); a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; promotes gene expression program that supports translational fidelity; evolutionarily-conserved adherin; relocalizes to cytosol in response to hypoxia; human disorder Cornelia de Lange syndrome is caused by mutations in NIPBL, the human ortholog of SCC2 [Source:SGD;Acc:S000002588]


Gene families : OG_03_0001670 (OF) Phylogenetic Tree(s): OG0001670_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YDR180W
Cluster HCCA: Cluster_21

Target Alias Description ECC score Gene Family Method Actions
EAU86150 No alias proline-rich protein Rad9 0.02 OF
EJF61054 No alias Sister chromatid cohesion C-terminus 0.02 OF
KHC76793 No alias cohesin loading factor subunit SCC2;HEAT repeat... 0.03 OF
POW11268 No alias Sister chromatid cohesion C-terminal domain;HEAT repeat... 0.05 OF
SPAC31A2.05c.1 No alias adherin, cohesin loading factor Mis4... 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR024986 Nipped-B_C 1205 1385
IPR026003 Cohesin_HEAT 721 762
No external refs found!