YDR158W

Description : Aspartic beta semi-aldehyde dehydrogenase; catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis [Source:SGD;Acc:S000002565]

Gene families : OG_03_0002943 (OF) Phylogenetic Tree(s): OG0002943_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR158W
Cluster	HCCA: Cluster_7

Target	Alias	Description	ECC score	Gene Family Method
AFR92389	No alias	aspartate-semialdehyde dehydrogenase;Semialdehyde...	0.02	OF
AOA68748	No alias	Semialdehyde dehydrogenase, dimerisation domain	0.21	OF
CAG80982	No alias	Semialdehyde dehydrogenase, NAD-binding	0.22	OF
CAK40824	No alias	Semialdehyde dehydrogenase, NAD binding domain	0.12	OF
CBF76771	No alias	aspartate-semialdehyde dehydrogenase	0.14	OF
EAA35479	No alias	Semialdehyde dehydrogenase, NAD-binding	0.18	OF
EAL92885	No alias	aspartate-semialdehyde dehydrogenase	0.14	OF
EAU82596	No alias	aspartate-semialdehyde dehydrogenase	0.04	OF
EDN98304	No alias	Semialdehyde dehydrogenase, dimerisation domain	0.05	OF
EGR47404	No alias	Semialdehyde dehydrogenase, dimerisation domain	0.14	OF
ESU14838	No alias	aspartate-semialdehyde dehydrogenase	0.15	OF
KHC81308	No alias	aspartate-semialdehyde dehydrogenase;"Semialdehyde...	0.17	OF
MGG_03051T0	No alias	Aspartate-semialdehyde dehydrogenase...	0.11	OF
SPCC1827.06c.1	No alias	aspartate semialdehyde dehydrogenase (predicted)...	0.13	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA	Interproscan
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046983	protein dimerization activity	IEA	Interproscan
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0051287	NAD binding	IEA	Interproscan
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR012280	Semialdhyde_DH_dimer_dom	165	345
IPR000534	Semialdehyde_DH_NAD-bd	7	130

External Links

No external refs found!

YDR158W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation