YDR120C

Description : tRNA methyltransferase; two forms of protein are made by alternative translation starts; localizes to both nucleus and mitochondrion to produce modified base N2,N2-dimethylguanosine in tRNAs in both compartments; nuclear Trm1p is evenly distributed around inner nuclear membrane in WT, but mislocalizes as puncta near ER-nucleus junctions in spindle pole body (SPB) mutants; both Trm1p inner nuclear membrane targeting and maintenance depend upon SPB [Source:SGD;Acc:S000002527]

Gene families : OG_03_0002005 (OF) Phylogenetic Tree(s): OG0002005_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR120C
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method
AFR92223	No alias	N2,N2-dimethylguanosine tRNA methyltransferase	0.02	OF
AOA68177	No alias	tRNA methyltransferase, Trm1	0.11	OF
CAG80206	No alias	tRNA methyltransferase, Trm1	0.11	OF
CAK36858	No alias	N2,N2-dimethylguanosine tRNA methyltransferase	0.16	OF
CBF87551	No alias	An-Trm1 protein related to S. cerevisiae Trm1	0.04	OF
EAA33134	No alias	tRNA methyltransferase, Trm1	0.05	OF
EAL86699	No alias	N2,N2-dimethylguanosine tRNA methyltransferase	0.05	OF
EAU88621	No alias	tRNA (guanine-N2-)-methyltransferase	0.03	OF
EDN98108	No alias	tRNA methyltransferase, Trm1	0.02	OF
ESU16316	No alias	tRNA methyltransferase, Trm1	0.12	OF
KHC71068	No alias	N2,N2-dimethylguanosine tRNA...	0.08	OF
POW02680	No alias	tRNA methyltransferase, Trm1	0.02	OF
SPBC25D12.05.1	No alias	tRNA (guanine-N2-)-methyltransferase Trm1...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008033	tRNA processing	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008170	N-methyltransferase activity	None	Extended
MF	GO:0008173	RNA methyltransferase activity	None	Extended
MF	GO:0008175	tRNA methyltransferase activity	None	Extended
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016423	tRNA (guanine) methyltransferase activity	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0034470	ncRNA processing	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR002905	Trm1	33	490

External Links

No external refs found!

YDR120C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation