Description : Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; role in DNA catenation/decatenation pathway of chromosome disentangling; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000000065]

Gene families : OG_03_0002782 (OF) Phylogenetic Tree(s): OG0002782_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YAR007C
Cluster HCCA: Cluster_33

Target Alias Description ECC score Gene Family Method Actions
AOA66855 No alias Replication factor-A protein 1, N-terminal 0.04 OF
CAG79583 No alias Replication factor A, C-terminal 0.02 OF
CAK37984 No alias Replication protein A OB domain 0.03 OF
CBF79351 No alias subunit of heterotrimeric Replication Factor 0.04 OF
EAA32097 No alias Replication factor-A protein 1, N-terminal 0.04 OF
EAL87723 No alias replication protein A 70 kDa DNA-binding subunit 0.02 OF
EGR53134 No alias OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 0.06 OF
KHC81114 No alias replication factor-a protein 1 (rpa1);Replication... 0.04 OF
MGG_00685T0 No alias Replication factor-A protein 1... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR031657 REPA_OB_2 306 400
IPR013955 Rep_factor-A_C 466 611
IPR004365 NA-bd_OB_tRNA 197 280
No external refs found!