YDR098C


Description : Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage; with Grx4p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; evidence exists indicating that the translation start site is not Met1 as currently annotated, but rather Met36; GRX3 has a paralog, GRX4, that arose from the whole genome duplication [Source:SGD;Acc:S000002505]


Gene families : OG_03_0001408 (OF) Phylogenetic Tree(s): OG0001408_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDR098C
Cluster HCCA: Cluster_57

Target Alias Description ECC score Gene Family Method Actions
MGG_06356T0 No alias Monothiol glutaredoxin-5 [Source:UniProtKB/TrEMBL;Acc:G4N7V1] 0.02 OF

Type GO Term Name Evidence Source
MF GO:0009055 electron transfer activity IEA Interproscan
MF GO:0015035 protein disulfide oxidoreductase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 14 100
IPR002109 Glutaredoxin 163 226
No external refs found!