YDR091C

Description : Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress [Source:SGD;Acc:S000002498]

Gene families : OG_03_0004033 (OF) Phylogenetic Tree(s): OG0004033_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR091C
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
AFR92884	No alias	ATP-binding cassette, sub-family E, member 1;ABC...	0.04	OF
AOA67786	No alias	ABC transporter-like	0.08	OF
CAG84114	No alias	ABC transporter-like	0.1	OF
CBF87844	No alias	RNase L inhibitor of the ABC superfamily, putative	0.05	OF
EAA34633	No alias	4Fe-4S ferredoxin-type, iron-sulphur binding domain	0.09	OF
EAL90359	No alias	RNase L inhibitor of the ABC superfamily, putative	0.03	OF
EAU89439	No alias	RNAse L inhibitor-type ATP binding cassette protein	0.03	OF
EJF59793	No alias	Possible Fer4-like domain in RNase L inhibitor, RLI	0.05	OF
ESU13296	No alias	translation initiation factor RLI1	0.06	OF
KHC83116	No alias	translation initiation factor RLI1;"Possible Fer4-like...	0.24	OF
MGG_11382T0	No alias	Translation initiation factor RLI1...	0.04	OF
POW09830	No alias	RNase L inhibitor RLI, possible metal-binding...	0.04	OF
SPBC14F5.06.1	No alias	iron-sulfur ATPase involved in ribosome biogenesis and...	0.07	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0008144	drug binding	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR007209	RNaseL-inhib_metal-bd_dom	7	37
IPR017896	4Fe4S_Fe-S-bd	50	71
IPR003439	ABC_transporter-like	374	496
IPR003439	ABC_transporter-like	101	249

External Links

No external refs found!

YDR091C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation