YDR091C


Description : Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress [Source:SGD;Acc:S000002498]


Gene families : OG_03_0004033 (OF) Phylogenetic Tree(s): OG0004033_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDR091C
Cluster HCCA: Cluster_8

Target Alias Description ECC score Gene Family Method Actions
AFR92884 No alias ATP-binding cassette, sub-family E, member 1;ABC... 0.04 OF
AOA67786 No alias ABC transporter-like 0.08 OF
CAG84114 No alias ABC transporter-like 0.1 OF
CBF87844 No alias RNase L inhibitor of the ABC superfamily, putative 0.05 OF
EAA34633 No alias 4Fe-4S ferredoxin-type, iron-sulphur binding domain 0.09 OF
EAL90359 No alias RNase L inhibitor of the ABC superfamily, putative 0.03 OF
EAU89439 No alias RNAse L inhibitor-type ATP binding cassette protein 0.03 OF
EJF59793 No alias Possible Fer4-like domain in RNase L inhibitor, RLI 0.05 OF
ESU13296 No alias translation initiation factor RLI1 0.06 OF
KHC83116 No alias translation initiation factor RLI1;"Possible Fer4-like... 0.24 OF
MGG_11382T0 No alias Translation initiation factor RLI1... 0.04 OF
POW09830 No alias RNase L inhibitor RLI, possible metal-binding... 0.04 OF
SPBC14F5.06.1 No alias iron-sulfur ATPase involved in ribosome biogenesis and... 0.07 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
MF GO:0016887 ATPase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR007209 RNaseL-inhib_metal-bd_dom 7 37
IPR017896 4Fe4S_Fe-S-bd 50 71
IPR003439 ABC_transporter-like 374 496
IPR003439 ABC_transporter-like 101 249
No external refs found!