Description : Subunit of the HOPS endocytic tethering complex; vacuole membrane protein that functions as a Rab GTPase effector, interacting specifically with the GTP-bound conformation of Ypt7p, facilitating tethering, docking and promoting membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking; Yck3p-mediated phosphorylation regulates the organization of vacuolar fusion sites [Source:SGD;Acc:S000002487]
Gene families : OG_03_0002555 (OF) Phylogenetic Tree(s): OG0002555_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR080W | |
Cluster | HCCA: Cluster_23 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
KHC83737 | No alias | hypothetical protein;Region in Clathrin and VPS | 0.02 | OF | |
SPAP27G11.05c.1 | No alias | HOPS complex subunit Vps41 (predicted)... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006886 | intracellular protein transport | IEA | Interproscan |
BP | GO:0016192 | vesicle-mediated transport | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000547 | Clathrin_H-chain/VPS_repeat | 754 | 898 |
No external refs found! |