Expression profile for YHR133C (YHR133C)

Description : Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; forms foci at the nuclear periphery upon DNA replication stress; relocalizes to the cytosol in response to hypoxia; homolog of mammalian INSIG proteins; NSG1 has a paralog, NSG2, that arose from the whole genome duplication [Source:SGD;Acc:S000001175]

Sample enrichment: 0.1 mm CuSO4,WT (SPM: 0.31, entropy: 3.64, tau: 0.59)
Perturbation specificity: Rapamycin (SPM: 0.39, entropy: 3.08, tau: 0.31)

All conditions

Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.