condition mean min max aqueous,WT 5.167104 1.75218 12.68 aqueous,KO_CRZ1 7.02528385 0.0787781 21.1644 aqueous 3.3384716666666665 1.07522 6.14644 aqueous,KO_CNA1 10.178472750000001 0.109291 15.8228 aqueous,KI_CNA1 7.644691666666667 1.53154 30.5148 Fungal cells,WT 128.33616766666665 0.857067 287.37 Fungal cells,rim101 KO,rim101 190.111 102.465 254.876 Fungal cells,cdc50 KO 81.3822 62.02 101.453 Yeast,Cuf1 401.3208333333333 165.733 608.938 Yeast,WT 215.90770454545455 15.9955 624.109 WT 160.63510744476596 4.18e-07 692.616 Yeast,YPD, 30C,matalpha 6.394758791 2.56e-07 98.9469 Yeast,YPG, 30C,matalpha 5.3600789008500005 2.69e-07 72.5655 V8, 25C,matalpha 7.172469922777778 2.12e-07 64.551 matalpha 17.891168587892857 7.58e-06 125.621 C. neoformans culture,WT 402.8231347826087 92.4631 664.341 Yeast 79.93148389030867 0.0 227.687 Mopane Tree 13.242014166666667 0.128305 56.5592 Pigeon Guano 5.731882325 0.0812891 35.7792 Clinical 3.4760558857142856 0.0364164 14.0983 CSF/HIV- 68.9546785 0.960994 1325.03 exp. evolved 2.4448549539591835 0.000651731 30.3233 CSF/HIV+ 13.198210572727273 0.0 78.5619 bronch. wash/HIV- 192.18569655555555 0.206641 857.937 rim101 1.47894 1.47894 1.47894 Yeast,ex vivo CSF 15.5112171855 0.000334371 31.0221 Yeast,in vivo CSF 177.33695 45.6849 308.989 Fungal cells,IP3 kinase KO 0.00021948533333333335 0.000110173 0.000309082 Fungal cells,IP5 kinase KO 0.012433108333333333 0.000251755 0.0315439 Fungal cells,IP6 kinase KO 0.00026294633333333333 0.000246679 0.000274351 Fungal cells,Parental strain 0.003322401 0.000213182 0.00952686 Cultured cells,inducing capsule,WT 177.339514925 5.97e-05 338.73 Cultured cells,inducing capsule,GAT201(CNAG_01551) OE 204.63033333333334 149.834 267.208 Cultured cells,inducing capsule,sp1(CNAG_00156) KO 118.056 112.861 123.818 Cultured cells,inducing capsule,usv101(CNAG_05420) KO 158.5085222222222 36.7745 293.277 Cultured cells,inducing capsule,P-CNAG_03437:GAT201(CNAG_01551) 343.15066666666667 296.012 434.326 Cultured cells,inducing capsule,P-CNAG_07442:GAT201(CNAG_01551) 309.29633333333334 258.093 370.725 YPD+sorbitol, 30C,WT KN99a 128.36295333333334 5.71106 303.183 YPD+sorbitol, 30C,BCK1 KO 125.55279999999999 4.3034 226.332 YPD+sorbitol, 30C,MKK2 KO 91.8914 44.1984 142.935 YPD+sorbitol, 30C 51.9575 51.9575 51.9575 H99 cdc24a,Pathogen 0.00014584125 1.15e-06 0.000247713 H99 cdc24b,Pathogen 0.0754203495 0.000104571 0.30116 H99 cdc42 420a,Pathogen 0.0001499495 1.01e-06 0.000252492 H99 cdc42 420b,Pathogen 0.000123138 9.63e-07 0.000244216 H99 HNa,Pathogen 0.000114004 2.67e-06 0.00021722 H99 HNb,Pathogen 0.000178949 1.95e-05 0.000239042 H99 ras_a,Pathogen 0.000132242 1.54e-05 0.000232345 H99 ras_b,Pathogen 0.00020301150000000002 9.28e-05 0.00024083 H99_a,Pathogen 2.995e-05 1.06e-05 5.21e-05 H99_b,Pathogen 9.164425000000001e-05 2.51e-05 0.000249677 H99 ptp3_a,Pathogen 0.00014107175 4.64e-05 0.000218009 H99 ptp3_b,Pathogen 6.528975e-05 3.04e-06 0.000213449 Pathogen 187.51425 111.598 285.732 Pathogen,WT 255.99075 166.273 327.974 YPD+H2O2,WT 51.9753 51.9753 51.9753 YPD+H2O2 434.407 434.407 434.407 Homosapien,Cryptococcal meningitis,Pathogen,WT 24.7461095 0.804518 63.052 Homosapien,Cryptococcal meningitis,Pathogen 6.744245 1.34129 12.1472 rich media; 2% glucose,SIR2 KO 0.16585284716666668 0.000564053 0.486671 calorie-restricted media; 0.05% glucose,WT 0.9880929333333334 0.0580106 4.18445 calorie-restricted media; 0.05% glucose,SIR2 KO 1.84894025 0.463705 4.80355 rich media; 2% glucose,WT 11.77819758 0.000711112 56.6832 CFO1::NEO 1.0828170415 0.000164083 2.16547 37C, CO2, 90 mins,WT 2.9688076666666667 0.143425 7.05022 37C, CO2, 90 mins 14.512021094727272 0.000623242 45.233 Fungal cells 49.45386666666667 16.0917 68.3647 Fungal cells,ssn801 KO 145.30083333333334 78.8565 203.522 Fungal cells,med13 KO 126.83126666666666 48.9158 208.573 Fungal cells,med12 KO 28.264390000000002 4.04847 69.1269 Fungal cells,cdk8 KO 29.12163333333333 18.961 44.9644 Fungal cells,kinase dead Cdk8 126.23723333333334 77.6037 159.556 Fungal cells,control Cdk8,WT 95.21963333333333 66.5409 146.65 bzp4 KO 0.00014273183333333333 1.7e-08 0.000430668 hob1 KO 0.05955079183333333 0.000312752 0.276671 mbs1 KO 0.006431126666666666 0.000167929 0.0366281 usv101 KO 0.036906786 0.000220945 0.156641 rad53 KO 430.3645 340.608 516.951 Fungal cells,hda1 KO 2.472143 0.871029 4.68877 Homosapien,Pathogen 91.04542934986841 1.74e-05 1860.54 cna02310::NAT 211.897625 122.963 302.113 PGPD1-ZNF2(D)-V5-NEO 288.112 116.739 482.391 dac2 KO 571.3346666666666 451.984 615.111 log. 30C 229.0491425 0.0 875.593 Homosapien,Pathogen,WT 6.3006505 0.74528 19.9536 cir1 KO 20.895987138166667 0.000166829 90.854 hapX KO 212.53845976666668 0.0928716 390.626 Homosapien,WT 5.84131 5.84131 5.84131 Homosapien,bwc1 1.41284 1.41284 1.41284 Fungal meningitis,Pathogen,matalpha 73.80675 26.0008 141.151 Fungal cells,pH4 68.0724880952381 2.48957 292.734 Fungal cells,pH4,sre1 KO 40.48451739130435 3.61767 134.183 Fungal cells,pH8 79.91627909090909 5.10605 372.387 Fungal cells,pH8,sre1 KO 125.27578695652174 3.36226 338.321