Sequence Description Alias PCC hrr YMR122C Putative protein of unknown function; conserved among S. cerevisiae strains; YMR122C is not an essential gene [Source:SGD;Acc:S000004729] 0.6635862054317517 2 YPL025C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000005946] 0.6269195864617844 3 YOR050C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; null mutant is viable [Source:SGD;Acc:S000005576] 0.6092484893334243 3 YBL044W Putative protein of unknown function; YBL044W is not an essential protein [Source:SGD;Acc:S000000140] 0.6048569059147988 4 YPR064W Putative protein of unknown function; conserved among S. cerevisiae strains; YPR064W is not an essential gene [Source:SGD;Acc:S000006268] 0.5866069491357514 5 YEL044W Component of the INO80 chromatin remodeling complex; critical for INO80 function; involved in regulation of chromosome segregation and maintenance of normal centromeric chromatin structure; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes [Source:SGD;Acc:S000000770] 0.584900484164404 6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; relocates to the cytosol under hypoxic conditions [Source:SGD;Acc:S000001017] 0.5787441373762702 32 YJL077C Protein with a role in copper homeostasis; possible role in vacuolar sorting and processing of secretory proteins; null mutants are hypersensitive to sortin2 [Source:SGD;Acc:S000003613] 0.5678899738773528 8 YER018C Component of the kinetochore-associated Ndc80 complex; involved in chromosome segregation, spindle checkpoint activity, and kinetochore clustering; evolutionarily conserved; other members include Ndc80p, Nuf2p, Spc24p, and Spc25p [Source:SGD;Acc:S000000820] 0.5368138542853697 25 YAL014C Endosomal SNARE related to mammalian syntaxin 8 [Source:SGD;Acc:S000000012] 0.5215508920444245 46 YML009W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; deletion mutation confers an increase in Ty1 transposition [Source:SGD;Acc:S000004471] 0.5121173067137229 12 YDR517W Acetylated cis-Golgi protein, involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002925] 0.5009558446222394 81 YIL154C Transcriptional activator involved in maintenance of ion homeostasis; also involved in protection against DNA damage caused by bleomycin and other oxidants; contains a C-terminal leucine-rich repeat [Source:SGD;Acc:S000001416] 0.49411444042987934 76 YOR376W Putative protein of unknown function; conserved among S. cerevisiae strains; YOR376W is not an essential gene [Source:SGD;Acc:S000005903] 0.48933428319670136 14 YHL019W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the verified gene APM2/YHL019C [Source:SGD;Acc:S000028772] 0.4763744270835841 21 YAL020C Protein required for modification of wobble nucleosides in tRNA; acts with Elongator complex, Kti11p, and Kti12p; has a potential role in regulatory interactions between microtubules and the cell cycle; forms a stable heterodimer with Kti11p [Source:SGD;Acc:S000000018] 0.46886164396840807 53 YBL006C Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions [Source:SGD;Acc:S000000102] 0.4653710736404757 36 YML116W-A Putative protein of unknown function [Source:SGD;Acc:S000004586] 0.4627145351178254 37 YKR075C Protein of unknown function; similar to Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; YKR075C has a paralog, YOR062C, that arose from the whole genome duplication [Source:SGD;Acc:S000001783] 0.4576112319200175 22 YCR025C Putative protein of unknown function; conserved across S. cerevisiae strains; YCR025C is not an essential gene [Source:SGD;Acc:S000000620] 0.4542704085380461 23 YGL126W Protein required for inositol prototrophy; required for normal ER membrane biosynthesis; ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis and homologous to human FIT2; disputed role in the synthesis of inositol phospholipids from inositol [Source:SGD;Acc:S000003094] 0.44995668097955865 32 YHR175W Low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation; regulated by nonsense-mediated mRNA decay pathway [Source:SGD;Acc:S000001218] 0.44433621471398277 57 YLR111W Putative protein of unknown function; conserved across S. cerevisiae strains [Source:SGD;Acc:S000004101] 0.44373631119139956 71 YLR099W-A Mitochondrial protein required for outer membrane protein import; involved in import of the subset of proteins with multiple alpha-helical transmembrane segments, including Ugo1p, Tom20p, and Fzo1p; component of a large protein complex in the outer membrane that includes Mim1p; not essential in W303 strain background [Source:SGD;Acc:S000007618] 0.4416166686089729 32 YPL062W Putative protein of unknown function; conserved across S. cerevisiae strains; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation [Source:SGD;Acc:S000005983] 0.43813987839005014 35 YLR350W Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; protein abundance increases in response to DNA replication stress; ORM2 has a paralog, ORM1, that arose from the whole genome duplication [Source:SGD;Acc:S000004342] 0.43769813520267625 67 YLR416C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000004408] 0.4368602498395104 38 YDR433W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000002841] 0.435917823921613 40 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization; organization includes assembly or stability; localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; interacts genetically with CYC1 and with cytochrome c oxidase assembly factors [Source:SGD;Acc:S000004208] 0.4198811442333689 51 YGR050C Protein of unknown function; mRNA identified as translated by ribosome profiling data [Source:SGD;Acc:S000003282] 0.4156794014285605 55 YLR112W Putative protein of unknown function; conserved across S. cerevisiae strains [Source:SGD;Acc:S000004102] 0.41429533841768734 56 YHR219W Putative protein of unknown function with similarity to helicases; located in the telomere region on the right arm of chromosome VIII [Source:SGD;Acc:S000001262] 0.41101761663093733 60 YGR137W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000003369] 0.4076886161294591 63 YDR476C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene [Source:SGD;Acc:S000002884] 0.4046706082321422 100 YHR210C Putative aldose 1-epimerase superfamily protein; non-essential gene; highly expressed under anaeorbic conditions [Source:SGD;Acc:S000001253] 0.400475223700999 71 YJL218W Putative acetyltransferase; similar to bacterial galactoside O-acetyltransferases; induced by oleate in an OAF1/PIP2-dependent manner; promoter contains an oleate response element consensus sequence; non-essential gene [Source:SGD;Acc:S000003754] 0.39970781253753657 72 YEL038W Protein with sequence similarity to acireductone synthases; involved in methionine salvage; found in both the cytoplasm and nucleus [Source:SGD;Acc:S000000764] 0.3984140722771236 73 YOR318C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo [Source:SGD;Acc:S000005845] 0.3853255743574806 89