Sequence Description Alias PCC hrr YML081C-A Subunit of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms [Source:SGD;Acc:S000007247] 0.7633382831145221 2 YMR256C Subunit VII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain [Source:SGD;Acc:S000004869] 0.6825559297028243 3 YDR003W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028819] 0.650420377661445 3 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex [Source:SGD;Acc:S000003415] 0.6502600767092597 9 YJL205C Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; SWAT-GFP and mCherry fusion proteins localize to the cytosol [Source:SGD;Acc:S000003742] 0.6465515515911195 5 YOR045W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005571] 0.635529549723167 6 YDR276C Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential [Source:SGD;Acc:S000002684] 0.6159152843222454 7 YJL127C-B Putative protein of unknown function; identified based on homology to the filamentous fungus, Ashbya gossypii; SWAT-GFP and seamless-GFP fusion proteins localize to the mitochondria [Source:SGD;Acc:S000028522] 0.5891553478296766 8 YMR251W-A Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor; HOR7 has a paralog, DDR2, that arose from the whole genome duplication [Source:SGD;Acc:S000004864] 0.5829630411288914 9 YFR010W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized gene YFR011C; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028824] 0.5538749430077741 10 YML054C-A Putative protein of unknown function [Source:SGD;Acc:S000028573] 0.5432985821446209 11 YOL052C-A Multi-stress response protein; expression is activated by a variety of xenobiotic agents and environmental or physiological stresses; DDR2 has a paralog, HOR7, that arose from the whole genome duplication [Source:SGD;Acc:S000005413] 0.5358517845601036 12 YDR119W-A Stabilizes or regulates formation of respiratory chain supercomplexes composed of Complex III (ubiquinol-cytochrome c reductase) and Complex IV (cytochrome c oxidase) [Source:SGD;Acc:S000113555] 0.5270628847731088 13 YPL189C-A Cytochrome oxidase assembly factor; null mutation results in respiratory deficiency with specific loss of cytochrome oxidase activity; functions downstream of assembly factors Mss51p and Coa1p and interacts with assembly factor Shy1p [Source:SGD;Acc:S000028527] 0.5202590638497508 14 YNL024C-A Essential protein suggested to function early in the secretory pathway; inviability is suppressed by overexpression of Golgi protein Tvp23p; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and cytosol respectively; ortholog of human Kish [Source:SGD;Acc:S000028698] 0.5152630905135992 15 YBR201C-A Putative protein of unknown function [Source:SGD;Acc:S000087085] 0.5066932589867573 16 YML007C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria [Source:SGD;Acc:S000007621] 0.5055536594161965 17 YPL271W Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated [Source:SGD;Acc:S000006192] 0.5012266767957724 35 YJL077W-B Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028662] 0.496335967729177 19 YJL133C-A Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000028805] 0.48889203011353816 20 YNL070W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005014] 0.48713791704298043 21 YPR010C-A Putative protein of unknown function; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the cytosol; conserved among Saccharomyces sensu stricto species [Source:SGD;Acc:S000122558] 0.4826664054458662 36 YPR133W-A Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore [Source:SGD;Acc:S000006433] 0.48042107532329537 23 YER053C-A Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000007523] 0.4698055712944144 24 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication [Source:SGD;Acc:S000000619] 0.4629857247656072 25 YBL100W-C Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028598] 0.46125614417992367 26 YOR376W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028586] 0.4549095204044531 27 YBR126W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-A; identified by SAGE [Source:SGD;Acc:S000028738] 0.4534486112470259 28 YMR158C-A Putative protein of unknown function; may contain a lipid attachment site; YMR158C-A is not an essential gene [Source:SGD;Acc:S000007249] 0.44481959481293754 29 YBL039W-B Putative protein of unknown function; mCherry fusion protein localizes to the vacuole [Source:SGD;Acc:S000028517] 0.4435484770120168 30 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p; binds to and inhibits GTP-bound Ras2p at the endoplasmic reticulum (ER); component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein [Source:SGD;Acc:S000028423] 0.44226859231967586 31 YKL162C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007244] 0.4362144258310708 32 YDR118W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified using a combination of expression profiling and mass spectrometry [Source:SGD;Acc:S000028820] 0.4361024581507628 33 YMR247W-A Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole [Source:SGD;Acc:S000028849] 0.43593345779780474 34 YIR018C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028837] 0.4291053174308578 35 YJL067W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000003603] 0.42538809847877046 90 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p [Source:SGD;Acc:S000003702] 0.4249227987623162 60 YBR200W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028535] 0.41535278553816085 38 YJL127W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007612] 0.40508047835748046 40 YCR095W-A Putative protein of unknown function [Source:SGD;Acc:S000029724] 0.401277171309036 41 YMR182W-A Putative protein of unknown function [Source:SGD;Acc:S000028693] 0.39925969316365884 42 YDR246W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028542] 0.39858954388058515 43 YBR085C-A Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000007522] 0.3866108095474084 88 YOL077W-A Subunit k of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase [Source:SGD;Acc:S000007339] 0.38070927668980126 47 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication [Source:SGD;Acc:S000002103] 0.3788907308424783 48 YGR174W-A Putative protein of unknown function; predicted to have a role in cell budding based on computational "guilt by association" analysis [Source:SGD;Acc:S000028639] 0.3782625986872957 49 YMR315W-A Putative protein of unknown function [Source:SGD;Acc:S000028697] 0.3756804070868523 50 YBR230W-A Putative protein of unknown function; YBR230W-A has a paralog, COQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000029722] 0.3596374576535338 52 YHR032C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YHR032W-A [Source:SGD;Acc:S000028646] 0.3577615366072169 53 YIL102C-A Putative protein of unknown function; identified based on comparisons of the genome sequences of six Saccharomyces species; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the endoplasmic reticulum [Source:SGD;Acc:S000113587] 0.3566534933376736 54 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex [Source:SGD;Acc:S000002391] 0.3562762272712419 55 YHL048C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028829] 0.34904735006593085 57 YKL163W O-glycosylated covalently-bound cell wall protein; required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; coding sequence contains length polymorphisms in different strains; PIR3 has a paralog, HSP150, that arose from the whole genome duplication [Source:SGD;Acc:S000001646] 0.3471463566189652 70 YBR209W Putative protein of unknown function; conserved across S. cerevisiae strains; YBR209W is not an essential gene [Source:SGD;Acc:S000000413] 0.34676346267061503 59 YDR034W-B Predicted tail-anchored plasma membrane protein; contains conserved CYSTM module; related proteins in other organisms may be involved in response to stress; N- and C-terminal fusion proteins localize to the cell periphery; YDR034W-B has a paralog, YBR056W-A, that arose from the whole genome duplication [Source:SGD;Acc:S000007234] 0.34330153402429414 60 YOR161C-C Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028712] 0.34092723826165966 61 YNL145W Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1 [Source:SGD;Acc:S000005089] 0.3360462009177743 62 YML058W Ribonucleotide reductase inhibitor; involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase; SML1 has a paralog, DIF1, that arose from the whole genome duplication [Source:SGD;Acc:S000004523] 0.3340484738161245 63 YPR036W-A Small (67 amino acids) protein involved in sporulation; localizes to the prospore membrane; phosphorylated during meiosis; a longer, 5'-extended mRNA is also transcribed beginning in mid-meiosis, regulated by two MSEs (middle sporulation elements), and includes an uORF of 15 codons in its 5'-UTR; evidence transcription is regulated by Pdr1p [Source:SGD;Acc:S000028425] 0.3338135031497587 64 YGR204C-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028640] 0.3306431507081411 65 YNL097C-B Putative protein of unknown function [Source:SGD;Acc:S000028699] 0.32843062895219016 66 YBR296C-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028605] 0.3180282336410656 70 YIL156W-B Putative protein of unknown function; originally identified based on homology to Ashbya gossypii and other related yeasts; SWAT-GFP and mCherry fusion proteins localize to the vacuole, while SWAT-GFP fusion also localizes to the endoplasmic reticulum [Source:SGD;Acc:S000028511] 0.3177215269826482 90 YHR175W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028553] 0.317115003180719 72 YNL277W-A Putative protein of unknown function [Source:SGD;Acc:S000028852] 0.3134947415541953 73 YDR510C-A Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028615] 0.3104591972767741 74 YGL188C-A Putative protein of unknown function [Source:SGD;Acc:S000028635] 0.3092259207696998 75 YOL038C-A Putative protein of unknown function; identified by SAGE analysis [Source:SGD;Acc:S000028812] 0.30595724787524725 78 YHR054W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps CUP1-2 [Source:SGD;Acc:S000028648] 0.30573621357623415 79 YHR052W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps CUP1-1 [Source:SGD;Acc:S000028647] 0.30573621357623415 80 YDR524W-C Putative protein of unknown function; small ORF identified by SAGE; deletion strains are moderately sensitive to the radiomimetic drug bleomycin [Source:SGD;Acc:S000028740] 0.3051278546488934 81 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; relocalizes to the cytosol in response to hypoxia; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair [Source:SGD;Acc:S000007603] 0.30417248079345793 82 YJL052C-A Putative protein of unknown function; identified based on comparison to related yeast species; mCherry fusion protein localizes to the vacuole [Source:SGD;Acc:S000007610] 0.3027045277011187 84 YFL041W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028547] 0.29980341323950366 87 YGR146C-A Putative protein of unknown function [Source:SGD;Acc:S000028638] 0.29730141654201975 89 YKL106C-A Putative protein of unknown function; identified by homology to uncharacterized proteins in other fungi [Source:SGD;Acc:S000007616] 0.2971494427407605 90 YML100W-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028688] 0.29407384054926916 93 YDR524C-A Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028616] 0.29052228524186546 95 YJL222W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000028664] 0.2886889944462654 97 YOR186W Putative protein of unknown function; proper regulation of expression during heat stress is sphingolipid-dependent; mCherry fusion protein localizes to the vacuole; YOR186W has a paralog, YLR297W, that arose from the whole genome duplication [Source:SGD;Acc:S000005712] 0.2861926966881882 99