Sequence Description Alias PCC hrr YLR242C Cortical ER protein; implicated in the membrane insertion of tail-anchored C-terminal single transmembrane domain proteins; may function in transport of glycosylphosphatidylinositol intermediates into the ER lumen; required for normal intracellular sterol distribution; human ARV1, required for normal cholesterol and bile acid homeostasis, can complement yeast arv1 null mutant; human variant causing early onset epileptic encephalopathy is unable to rescue the yeast null [Source:SGD;Acc:S000004232] 0.5599265811399075 11 YJL059W Protein required for the ATP-dependent transport of arginine; vacuolar membrane protein; involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; human homolog CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis) can complement yeast null mutant [Source:SGD;Acc:S000003595] 0.520980271813525 13 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase); dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions [Source:SGD;Acc:S000003900] 0.46996523675623375 28 YIL114C Putative mitochondrial porin (voltage-dependent anion channel); not required for mitochondrial membrane permeability or mitochondrial osmotic stability; POR2 has a paralog, POR1, that arose from the whole genome duplication [Source:SGD;Acc:S000001376] 0.4209830127755643 84 YDR367W Component of inositol phosphorylceramide (IPC) synthase; forms a complex with Aur1p and regulates its activity; required for IPC synthase complex localization to the Golgi; post-translationally processed by Kex2p; KEI1 is an essential gene [Source:SGD;Acc:S000002775] 0.42094024431033883 60 YGL054C COPII-coated vesicle protein; involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p and Nha1p antiporter to cell surface; related to Drosophila cornichon; ERV14 has a paralog, ERV15, that arose from the whole genome duplication [Source:SGD;Acc:S000003022] 0.4186062758559648 36 YEL028W Putative protein of unknown function; conserved among S. cerevisiae strains; YEL028C is not an essential gene [Source:SGD;Acc:S000000754] 0.398379066112554 47 YJL196C Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication [Source:SGD;Acc:S000003732] 0.3869188628047174 59 YOL097W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028854] 0.386558735335156 61 YGL204C Protein of unknown function; mRNA identified as translated by ribosome profiling data; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum [Source:SGD;Acc:S000003172] 0.385426726702867 63 YJL022W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PET130 [Source:SGD;Acc:S000003559] 0.372566606630189 80