Sequence Description Alias PCC hrr YLR161W Putative protein of unknown function; YLR156W, YLR159W, and YLR161W are three identical open reading frames in S288C encoded near the ribosomal DNA region of chromosome 12; YLR161W has a paralog, YLR157W-D, that arose from a segmental duplication [Source:SGD;Acc:S000004151] 0.9999999999999838 2 YLR159W Putative protein of unknown function; YLR156W, YLR159W, and YLR161W are three identical open reading frames in S288C encoded near the ribosomal DNA region of chromosome 12; YLR159W has a paralog, YLR156W, that arose from a segmental duplication [Source:SGD;Acc:S000004149] 0.9999999999999838 2 YCL068C Putative protein of unknown function [Source:SGD;Acc:S000000573] 0.5829907011374371 4 YDR136C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 4% of ORF overlaps the verified gene RGP1; deletion causes a vacuolar protein sorting defect [Source:SGD;Acc:S000002543] 0.5484195053532734 8 YPL003W Protein that activates Rub1p (NEDD8) before neddylation; acts together with Uba3p; may play a role in protein degradation [Source:SGD;Acc:S000005924] 0.5258358336601135 54 YOL114C Protein similar to the human peptidyl-tRNA hydrolase gene ICT1; associates with mitochondrial large subunit; may function in translation termination; YOL114C is not an essential gene [Source:SGD;Acc:S000005474] 0.5167444862594871 8 YLR031W Putative protein of unknown function; S288C contains an in-frame stop codon between ORFs YLR030W and YLR031W; YLR031W has a paralog, YMR124W, that arose from the whole genome duplication [Source:SGD;Acc:S000004021] 0.5111446178285122 10 YMR222C Putative serine hydrolase that localizes to the cytoplasm; sequence is similar to S. cerevisiae Fsh1p and Fsh3p and the human candidate tumor suppressor OVCA2 [Source:SGD;Acc:S000004835] 0.4877389655493293 9 YIL132C Component of Shu complex (aka PCSS complex); Shu complex also includes Psy3, Shu1, Shu2, and promotes error-free DNA repair,; Shu complex mediates inhibition of Srs2p function; promotes formation of Rad51p filaments; Psy3p and Csm2p contain similar DNA-binding regions which work together to form a single DNA binding site; required for accurate chromosome segregation during meiosis [Source:SGD;Acc:S000001394] 0.45580377643168607 26 YDR112W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps ALT2/YDR111C; null mutant displays increased levels of spontaneous Rad52p foci [Source:SGD;Acc:S000002519] 0.41413081848305605 14 YGL034C Putative protein of unknown function; conserved among S. cerevisiae strains; YGL034C is not an essential gene [Source:SGD;Acc:S000003002] 0.40431969638639076 99 YNL211C Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL211C is not an essential gene [Source:SGD;Acc:S000005155] 0.39140471987610553 20 YIL012W Putative protein of unknown function; conserved across S. cerevisiae strains [Source:SGD;Acc:S000001274] 0.37820109229173987 92 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants [Source:SGD;Acc:S000003778] 0.377767261627372 74 YJL027C Putative protein of unknown function [Source:SGD;Acc:S000003564] 0.34803032736828143 84 YGR039W Putative protein of unknown function; conserved among S. cerevisiae strains; YGR039W is not an essential gene [Source:SGD;Acc:S000003271] 0.34618184149337217 41 YJR129C S-adenosylmethionine-dependent methyltransferase; seven-beta-strand lysine methyltransferase which trimethylates translation elongation factor EF2 (Eft1p and Eft2p) at lysine 509; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; ortholog of human gene FAM86A [Source:SGD;Acc:S000003890] 0.338584782812891 54 YOR376W Putative protein of unknown function; conserved among S. cerevisiae strains; YOR376W is not an essential gene [Source:SGD;Acc:S000005903] 0.33452802497693895 97