Sequence Description Alias PCC hrr YOR029W Putative protein of unknown function; conserved among S. cerevisiae strains; YOR029W is not an essential gene [Source:SGD;Acc:S000005555] 0.7332077845715728 4 YOR298W Protein of unknown function involved in outer spore wall organization; has similarity to the tafazzins superfamily of acyltransferases [Source:SGD;Acc:S000005824] 0.7110345177091387 2 YGR056W Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook; RSC1 has a paralog, RSC2, that arose from the whole genome duplication [Source:SGD;Acc:S000003288] 0.6963905872088502 22 YDR344C Putative protein of unknown function; conserved among S. cerevisiae strains [Source:SGD;Acc:S000002752] 0.6961247383771602 4 YPL241C GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; human homolog RP2 complements yeast null mutant [Source:SGD;Acc:S000006162] 0.69526531627674 5 YBR007C Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000211] 0.6907975045229702 21 YHR093W Putative protein of unknown function; conserved across S. cerevisiae strains; not conserved in closely related Saccharomyces species; multicopy suppressor of glucose transport defects, likely due to the presence of an HXT4 regulatory element in the region [Source:SGD;Acc:S000001135] 0.6848781824540872 9 YGR212W N-acetyltransferase; confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin [Source:SGD;Acc:S000003444] 0.6845268489571718 8 YLR112W Putative protein of unknown function; conserved across S. cerevisiae strains [Source:SGD;Acc:S000004102] 0.6576163119149501 9 YNL028W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000004973] 0.6402572260705787 10 YPL025C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000005946] 0.6396148928842433 11 YCR100C Putative protein of unknown function [Source:SGD;Acc:S000000697] 0.6326232783772423 20 YBL065W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified ORF SEF1/YBL066C; YBL065W is a non-essential gene [Source:SGD;Acc:S000000161] 0.6263711565567406 13 YCR101C Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene [Source:SGD;Acc:S000000698] 0.6110375562434434 29 YHR177W Putative transcription factor containing a WOPR domain; binds DNA in vitro; similar to C. albicans Wor1p transcription factor that regulates white-opaque switching; overexpression causes a cell cycle delay or arrest [Source:SGD;Acc:S000001220] 0.6065435370928455 15 YDR215C Putative protein of unknown function; conserved across S. cerevisiae strains; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein [Source:SGD;Acc:S000002623] 0.5962237541316753 16 YFR054C Putative protein of unknown function; conserved among S. cerevisiae strains [Source:SGD;Acc:S000001950] 0.589596895468406 17 YIL025C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000001287] 0.5895320078898048 18 YDR108W Component of transport protein particle (TRAPP) complex III; TRAPPIII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating endosome-Golgi traffic and required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role [Source:SGD;Acc:S000002515] 0.573522976535127 75 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p; stimulates the GTPase activity of Rag family GTPase Gtr2p, within the context of the Gtr1p-Gtr2p heterodimer, after amino acid stimulation; required for activation of TORC1 in response to amino acid stimulation; recruited to the vacuolar membrane during amino acid starvation and released from the membrane by TORC1; required for the transport of amino acid permease Gap1p from the Golgi to the cell surface [Source:SGD;Acc:S000003289] 0.564336721893143 34 YLL063C Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis [Source:SGD;Acc:S000003986] 0.5528029082544603 34 YOR368W Checkpoint protein; involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins [Source:SGD;Acc:S000005895] 0.5518154409289479 99 YCR022C Putative protein of unknown function; conserved among S. cerevisiae strains; YCR022C is not an essential gene [Source:SGD;Acc:S000000616] 0.5456082503283516 26 YDR107C Protein with a role in cellular adhesion and filamentous growth; similar to Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments; TMN2 has a paralog, EMP70, that arose from the whole genome duplication [Source:SGD;Acc:S000002514] 0.5435502473271797 47 YDR501W Putative transcription factor, contains Forkhead Associated domain; found associated with chromatin; target of SBF transcription factor; induced in response to DNA damaging agents and deletion of telomerase; PLM2 has a paralog, TOS4, that arose from the whole genome duplication [Source:SGD;Acc:S000002909] 0.5426961206067547 38 YGR107W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000003339] 0.5423576463477481 29 YDR066C Protein of unknown function; exhibits genetic interactions with Rtr1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR066C is not an essential gene; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; RTR2 has a paralog, RTR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002473] 0.5391075944736822 70 YHR054C Putative protein of unknown function; partial duplicate of RSC30/YHR056C, truncated remnant of segmental duplication [Source:SGD;Acc:S000001096] 0.5299955621104867 34 YNL105W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified gene INP52; identified in a screen for mutants with decreased levels of rDNA transcription [Source:SGD;Acc:S000005049] 0.5265208679255564 37 YHR176W Flavin-containing monooxygenase; localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins [Source:SGD;Acc:S000001219] 0.5211739507919532 38 YOR297C Component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane; may mediate assembly or stability of the complex [Source:SGD;Acc:S000005823] 0.5169288247307904 40 YCR099C Putative protein of unknown function [Source:SGD;Acc:S000000696] 0.5134667263953276 41 YHR213W-B Pseudogenic fragment with similarity to flocculins; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; YHR213W-B has a paralog, YAR064W, that arose from a segmental duplication [Source:SGD;Acc:S000028652] 0.5017842842888052 47 YBL073W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the essential gene AAR2/YBL074C [Source:SGD;Acc:S000000169] 0.49544742942240605 49 YHL037C Putative protein of unknown function; conserved among S. cerevisiae strains [Source:SGD;Acc:S000001029] 0.48137602020582065 55 YIL054W Protein of unknown function; expressed at both mRNA and protein levels [Source:SGD;Acc:S000001316] 0.48041645029512864 56 YER104W Protein with a role in regulation of Ty1 transposition [Source:SGD;Acc:S000000906] 0.46716074991512796 61 YLR416C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000004408] 0.46682856504036524 62 YJL182C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YJL181W [Source:SGD;Acc:S000003718] 0.45423652960403466 64 YIL141W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000001403] 0.4487980586738868 92 YDR078C Component of Shu complex (aka PCSS complex); Shu complex also includes Psy3, Csm2, Shu1, and promotes error-free DNA repair, Shu complex mediates inhibition of Srs2p function; promotes formation of Rad51p filaments; important for both mitotic and meiotic homologous recombination, and contains a conserved SWIM domain that is necessary for both [Source:SGD;Acc:S000002485] 0.44751695648601175 69 YCL027W Membrane protein localized to the shmoo tip; required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate [Source:SGD;Acc:S000000532] 0.44476179578328867 94 YKL037W Protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss; null mutation confers sensitivity to tunicamycin and DTT [Source:SGD;Acc:S000001520] 0.44373631119139956 71 YOR318C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo [Source:SGD;Acc:S000005845] 0.4417915541985022 72 YFL015W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps ORF YFL015C [Source:SGD;Acc:S000028765] 0.44167536996794343 73 YOR050C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; null mutant is viable [Source:SGD;Acc:S000005576] 0.4299551417070913 81 YMR317W Putative protein of unknown function; has some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene [Source:SGD;Acc:S000004936] 0.42895714910192717 82 YNL198C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000005142] 0.42221693332887245 87 YJL135W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified genes YJL134W/LCB3 [Source:SGD;Acc:S000003671] 0.4180935100385606 91 YPR064W Putative protein of unknown function; conserved among S. cerevisiae strains; YPR064W is not an essential gene [Source:SGD;Acc:S000006268] 0.4159862015671482 93