Sequence Description Alias PCC hrr YEL038W Protein with sequence similarity to acireductone synthases; involved in methionine salvage; found in both the cytoplasm and nucleus [Source:SGD;Acc:S000000764] 0.5224534538350427 6 YMR103C Putative protein of unknown function; conserved among S. cerevisiae strains; YMR103C is not an essential gene [Source:SGD;Acc:S000004709] 0.48907127189292293 12 YDR433W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000002841] 0.46153549380934605 5 YDR209C Putative protein of unknown function; conserved among S. cerevisiae strains; YDR209C is not an essential gene; partially overlaps uncharacterized gene YDR210W [Source:SGD;Acc:S000002617] 0.4458831881861598 60 YAL020C Protein required for modification of wobble nucleosides in tRNA; acts with Elongator complex, Kti11p, and Kti12p; has a potential role in regulatory interactions between microtubules and the cell cycle; forms a stable heterodimer with Kti11p [Source:SGD;Acc:S000000018] 0.439154087369106 78 YPR087W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene SRP54; deletion causes a vacuolar protein sorting defect [Source:SGD;Acc:S000006291] 0.4216759228237362 39 YKL037W Protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss; null mutation confers sensitivity to tunicamycin and DTT [Source:SGD;Acc:S000001520] 0.4076886161294591 63 YGL126W Protein required for inositol prototrophy; required for normal ER membrane biosynthesis; ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis and homologous to human FIT2; disputed role in the synthesis of inositol phospholipids from inositol [Source:SGD;Acc:S000003094] 0.40006123713070146 67 YMR294W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; substantially overlaps YMR295C; deletion causes sensitivity to unfolded protein response-inducing agents [Source:SGD;Acc:S000004909] 0.3904084710360647 38 YML009W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; deletion mutation confers an increase in Ty1 transposition [Source:SGD;Acc:S000004471] 0.38847927328973486 67 YML028W Thioredoxin peroxidase; acts as both ribosome-associated and free cytoplasmic antioxidant; self-associates to form high-molecular weight chaperone complex under oxidative stress; chaperone activity essential for growth in zinc deficiency; required for telomere length maintenance; binds and modulates Cdc19p activity; protein abundance increases, forms cytoplasmic foci during DNA replication stress; TSA1 has a paralog, TSA2, that arose from the whole genome duplication [Source:SGD;Acc:S000004490] 0.37937063958097245 81 YJL077C Protein with a role in copper homeostasis; possible role in vacuolar sorting and processing of secretory proteins; null mutants are hypersensitive to sortin2 [Source:SGD;Acc:S000003613] 0.37108028133342696 78 YLR109W Thiol-specific peroxiredoxin; reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p [Source:SGD;Acc:S000004099] 0.37091297045850025 63 YPR064W Putative protein of unknown function; conserved among S. cerevisiae strains; YPR064W is not an essential gene [Source:SGD;Acc:S000006268] 0.34931571390381877 98 YMR122W-A Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and endoplasmic reticulum [Source:SGD;Acc:S000007524] 0.34914769744984997 100