Sequence Description Alias PCC hrr YML081C-A Subunit of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms [Source:SGD;Acc:S000007247] 0.7448671666929713 3 YOR045W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005571] 0.6603374456854917 2 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain [Source:SGD;Acc:S000002225] 0.6465515515911195 5 YMR251W-A Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor; HOR7 has a paralog, DDR2, that arose from the whole genome duplication [Source:SGD;Acc:S000004864] 0.5808314478897771 4 YDR003W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028819] 0.5698957178089881 7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain [Source:SGD;Acc:S000004869] 0.5476467107226178 11 YMR158C-A Putative protein of unknown function; may contain a lipid attachment site; YMR158C-A is not an essential gene [Source:SGD;Acc:S000007249] 0.5469585695403029 7 YDR276C Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential [Source:SGD;Acc:S000002684] 0.5461403506979425 11 YPL271W Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated [Source:SGD;Acc:S000006192] 0.5226088056795788 26 YBR126W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-A; identified by SAGE [Source:SGD;Acc:S000028738] 0.5211433390299897 10 YJL127C-B Putative protein of unknown function; identified based on homology to the filamentous fungus, Ashbya gossypii; SWAT-GFP and seamless-GFP fusion proteins localize to the mitochondria [Source:SGD;Acc:S000028522] 0.5202305790476295 11 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex [Source:SGD;Acc:S000003415] 0.5129510509364079 28 YER053C-A Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000007523] 0.5116445646320975 13 YFR010W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized gene YFR011C; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028824] 0.5069355836799732 14 YNL070W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005014] 0.4996920372757741 15 YBL039W-B Putative protein of unknown function; mCherry fusion protein localizes to the vacuole [Source:SGD;Acc:S000028517] 0.4943153795179576 16 YNL024C-A Essential protein suggested to function early in the secretory pathway; inviability is suppressed by overexpression of Golgi protein Tvp23p; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and cytosol respectively; ortholog of human Kish [Source:SGD;Acc:S000028698] 0.4909422219074212 17 YML007C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria [Source:SGD;Acc:S000007621] 0.48192400946499236 18 YOL052C-A Multi-stress response protein; expression is activated by a variety of xenobiotic agents and environmental or physiological stresses; DDR2 has a paralog, HOR7, that arose from the whole genome duplication [Source:SGD;Acc:S000005413] 0.480822473871634 19 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p; binds to and inhibits GTP-bound Ras2p at the endoplasmic reticulum (ER); component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein [Source:SGD;Acc:S000028423] 0.47749322784864634 20 YDR119W-A Stabilizes or regulates formation of respiratory chain supercomplexes composed of Complex III (ubiquinol-cytochrome c reductase) and Complex IV (cytochrome c oxidase) [Source:SGD;Acc:S000113555] 0.4723622744044148 21 YML054C-A Putative protein of unknown function [Source:SGD;Acc:S000028573] 0.4617982611374434 22 YJL133C-A Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000028805] 0.4555192674623235 23 YKL162C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007244] 0.44039426429969275 24 YHL048C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028829] 0.4359552975095005 25 YDR118W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified using a combination of expression profiling and mass spectrometry [Source:SGD;Acc:S000028820] 0.43477884993960486 26 YBR230W-A Putative protein of unknown function; YBR230W-A has a paralog, COQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000029722] 0.4166660037770642 27 YGR174W-A Putative protein of unknown function; predicted to have a role in cell budding based on computational "guilt by association" analysis [Source:SGD;Acc:S000028639] 0.41482773956310226 28 YPL189C-A Cytochrome oxidase assembly factor; null mutation results in respiratory deficiency with specific loss of cytochrome oxidase activity; functions downstream of assembly factors Mss51p and Coa1p and interacts with assembly factor Shy1p [Source:SGD;Acc:S000028527] 0.41401902424564935 41 YMR182W-A Putative protein of unknown function [Source:SGD;Acc:S000028693] 0.4078602833410435 30 YJL127W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007612] 0.394618842681526 31 YBL100W-C Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028598] 0.3943337133191508 32 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication [Source:SGD;Acc:S000000619] 0.38825994572207084 39 YMR247W-A Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole [Source:SGD;Acc:S000028849] 0.3881262746074233 34 YBR200W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028535] 0.3871844989608604 35 YCR095W-A Putative protein of unknown function [Source:SGD;Acc:S000029724] 0.38505496674670553 36 YKL106C-A Putative protein of unknown function; identified by homology to uncharacterized proteins in other fungi [Source:SGD;Acc:S000007616] 0.3848108086359567 37 YJL077W-B Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028662] 0.38271006665536517 38 YIR018C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028837] 0.381533084961746 39 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication [Source:SGD;Acc:S000002103] 0.3658383244098866 40 YMR315W-A Putative protein of unknown function [Source:SGD;Acc:S000028697] 0.3632341629444174 41 YDR034W-B Predicted tail-anchored plasma membrane protein; contains conserved CYSTM module; related proteins in other organisms may be involved in response to stress; N- and C-terminal fusion proteins localize to the cell periphery; YDR034W-B has a paralog, YBR056W-A, that arose from the whole genome duplication [Source:SGD;Acc:S000007234] 0.3626444396461099 42 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex [Source:SGD;Acc:S000002391] 0.36085572110127434 43 YNL145W Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1 [Source:SGD;Acc:S000005089] 0.35799391402131875 44 YBR201C-A Putative protein of unknown function [Source:SGD;Acc:S000087085] 0.3562417025301399 51 YFL041W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028547] 0.3543411796616545 46 YIL156W-B Putative protein of unknown function; originally identified based on homology to Ashbya gossypii and other related yeasts; SWAT-GFP and mCherry fusion proteins localize to the vacuole, while SWAT-GFP fusion also localizes to the endoplasmic reticulum [Source:SGD;Acc:S000028511] 0.3531286192906983 52 YOR186W Putative protein of unknown function; proper regulation of expression during heat stress is sphingolipid-dependent; mCherry fusion protein localizes to the vacuole; YOR186W has a paralog, YLR297W, that arose from the whole genome duplication [Source:SGD;Acc:S000005712] 0.35192461242786044 48 YLR466C-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000028686] 0.34420403961879287 49 YHR175W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028553] 0.3421355624537894 50 YKL163W O-glycosylated covalently-bound cell wall protein; required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; coding sequence contains length polymorphisms in different strains; PIR3 has a paralog, HSP150, that arose from the whole genome duplication [Source:SGD;Acc:S000001646] 0.3403620200156741 76 YOR376W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028586] 0.33964660171837424 52 YHR032C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YHR032W-A [Source:SGD;Acc:S000028646] 0.3380392741250785 53 YEL050W-A Dubious open reading frame unlikely to encode a functional protein; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028545] 0.3340968050379764 54 YBR209W Putative protein of unknown function; conserved across S. cerevisiae strains; YBR209W is not an essential gene [Source:SGD;Acc:S000000413] 0.33276476946362427 64 YOL038C-A Putative protein of unknown function; identified by SAGE analysis [Source:SGD;Acc:S000028812] 0.3317456883145582 56 YDR246W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028542] 0.3170146881041758 58 YPR133W-A Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore [Source:SGD;Acc:S000006433] 0.30445042728850663 61 YHR054W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps CUP1-2 [Source:SGD;Acc:S000028648] 0.3010876031661255 63 YHR052W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps CUP1-1 [Source:SGD;Acc:S000028647] 0.3010876031661255 64 YJL052C-A Putative protein of unknown function; identified based on comparison to related yeast species; mCherry fusion protein localizes to the vacuole [Source:SGD;Acc:S000007610] 0.30100206551635217 65 YOR161C-C Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028712] 0.2973531741408531 66 YNL097C-B Putative protein of unknown function [Source:SGD;Acc:S000028699] 0.2940846369783716 69 YGL188C-A Putative protein of unknown function [Source:SGD;Acc:S000028635] 0.29260635425106013 71 YML058W Ribonucleotide reductase inhibitor; involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase; SML1 has a paralog, DIF1, that arose from the whole genome duplication [Source:SGD;Acc:S000004523] 0.2904978651952948 92 YMR046W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007248] 0.28899756329811843 75 YGR146C-A Putative protein of unknown function [Source:SGD;Acc:S000028638] 0.2850556362155789 76 YOL077W-A Subunit k of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase [Source:SGD;Acc:S000007339] 0.28467285260315206 77 YER175W-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028625] 0.2818138786563905 80 YFR032C-A Ribosomal 60S subunit protein L29; not essential for translation, but required for proper joining of large and small ribosomal subunits and for normal translation rate; homologous to mammalian ribosomal protein L29, no bacterial homolog [Source:SGD;Acc:S000006437] 0.2794236279338627 82 YNL277W-A Putative protein of unknown function [Source:SGD;Acc:S000028852] 0.27234738128797137 85 YDR524W-C Putative protein of unknown function; small ORF identified by SAGE; deletion strains are moderately sensitive to the radiomimetic drug bleomycin [Source:SGD;Acc:S000028740] 0.2704945821599528 86 YIL102C-A Putative protein of unknown function; identified based on comparisons of the genome sequences of six Saccharomyces species; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the endoplasmic reticulum [Source:SGD;Acc:S000113587] 0.26408159340494186 88 YOR182C Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S30, no bacterial homolog; RPS30B has a paralog, RPS30A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005708] 0.26273516679322056 89 YER138W-A Putative protein of unknown function; YER138W-A has a paralog, YBL107W-A, that arose from a single-locus duplication [Source:SGD;Acc:S000007239] 0.2623333164985269 90 YDL061C Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S29 and bacterial S14; RPS29B has a paralog, RPS29A, that arose from the whole genome duplication [Source:SGD;Acc:S000002219] 0.26084356559599925 92 YDR510C-A Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028615] 0.25842728217667554 93 YLR402W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000004394] 0.25473382336638933 94 YOR008W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007628] 0.25360305488028384 95 YKL096C-B Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028667] 0.2506115400940754 96 YDR461W Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2 [Source:SGD;Acc:S000002869] 0.24490501934648876 99