Sequence Description Alias PCC hrr YIL166C Putative protein with similarity to allantoate permease; similar to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene [Source:SGD;Acc:S000001428] 0.5995570004128553 1 YLL062C S-methylmethionine-homocysteine methyltransferase; functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio [Source:SGD;Acc:S000003985] 0.5783371419598006 11 YDL059C Protein involved DNA double-strand break repair; repairs breaks in DNA during vegetative growth via recombination and single-strand annealing; anneals complementary single-stranded DNA; forms nuclear foci upon DNA replication stress; required for loading of Rad52p to DSBs; regulates replication fork progression in DNA ligase I-deficient cells; paralog of Rad52p [Source:SGD;Acc:S000002217] 0.5697090125692263 23 YPL241C GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; human homolog RP2 complements yeast null mutant [Source:SGD;Acc:S000006162] 0.5689965875492984 34 YBR007C Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000211] 0.5528929609332951 77 YBL065W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified ORF SEF1/YBL066C; YBL065W is a non-essential gene [Source:SGD;Acc:S000000161] 0.5453809121985578 18 YDR066C Protein of unknown function; exhibits genetic interactions with Rtr1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR066C is not an essential gene; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; RTR2 has a paralog, RTR1, that arose from the whole genome duplication [Source:SGD;Acc:S000002473] 0.5388154996882315 71 YDR253C Zinc-finger DNA-binding transcription factor; involved in transcriptional regulation of the methionine biosynthetic genes; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; lack of such a loop for MET31 may account for the differential actions of Met32p and Met31p; MET32 has a paralog, MET31, that arose from the whole genome duplication [Source:SGD;Acc:S000002661] 0.5362214556542038 18 YCR100C Putative protein of unknown function [Source:SGD;Acc:S000000697] 0.5240779574555859 67 YHR093W Putative protein of unknown function; conserved across S. cerevisiae strains; not conserved in closely related Saccharomyces species; multicopy suppressor of glucose transport defects, likely due to the presence of an HXT4 regulatory element in the region [Source:SGD;Acc:S000001135] 0.5221155974550515 47 YLR111W Putative protein of unknown function; conserved across S. cerevisiae strains [Source:SGD;Acc:S000004101] 0.5211739507919532 38 YAL037W Putative protein of unknown function; YAL037W has a paralog, YOR342C, that arose from the whole genome duplication [Source:SGD;Acc:S000000035] 0.5081379652580192 27 YBL073W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the essential gene AAR2/YBL074C [Source:SGD;Acc:S000000169] 0.5056389366615837 23 YHR112C Protein of unknown function; localizes to the cytoplasm and nucleus; overexpression affects protein trafficking through the endocytic pathway [Source:SGD;Acc:S000001154] 0.4899489409957354 21 YHR177W Putative transcription factor containing a WOPR domain; binds DNA in vitro; similar to C. albicans Wor1p transcription factor that regulates white-opaque switching; overexpression causes a cell cycle delay or arrest [Source:SGD;Acc:S000001220] 0.4870149244461494 98 YCR101C Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene [Source:SGD;Acc:S000000698] 0.48196348302618497 92 YOR029W Putative protein of unknown function; conserved among S. cerevisiae strains; YOR029W is not an essential gene [Source:SGD;Acc:S000005555] 0.4777218720619411 76 YLL055W High-affinity cysteine-specific transporter; has similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene [Source:SGD;Acc:S000003978] 0.47696921763308237 32 YLL058W Putative protein of unknown function with similarity to Str2p; Str2p is a cystathionine gamma-synthase important in sulfur metabolism; YLL058W is not an essential gene [Source:SGD;Acc:S000003981] 0.4718841067174181 33 YNL277W L-homoserine-O-acetyltransferase; catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway [Source:SGD;Acc:S000005221] 0.45970526682462853 65 YJR010W ATP sulfurylase; catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism; human homolog PAPSS2 complements yeast null mutant [Source:SGD;Acc:S000003771] 0.45891633400734655 41 YEL072W Protein required for sporulation [Source:SGD;Acc:S000000798] 0.4539310397414892 59 YHR213W-B Pseudogenic fragment with similarity to flocculins; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; YHR213W-B has a paralog, YAR064W, that arose from a segmental duplication [Source:SGD;Acc:S000028652] 0.44609578403977673 50 YOR298W Protein of unknown function involved in outer spore wall organization; has similarity to the tafazzins superfamily of acyltransferases [Source:SGD;Acc:S000005824] 0.4451097247614815 91 YIL025C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000001287] 0.4410749134998364 68 YLR364W Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic [Source:SGD;Acc:S000004356] 0.4333577870278093 59 YIL054W Protein of unknown function; expressed at both mRNA and protein levels [Source:SGD;Acc:S000001316] 0.4312526674479894 61 YDR344C Putative protein of unknown function; conserved among S. cerevisiae strains [Source:SGD;Acc:S000002752] 0.42440680977957534 100 YKL001C Adenylylsulfate kinase; required for sulfate assimilation and involved in methionine metabolism; human homolog PAPSS2 complements yeast null mutant [Source:SGD;Acc:S000001484] 0.41399845613489733 77 YDR078C Component of Shu complex (aka PCSS complex); Shu complex also includes Psy3, Csm2, Shu1, and promotes error-free DNA repair, Shu complex mediates inhibition of Srs2p function; promotes formation of Rad51p filaments; important for both mitotic and meiotic homologous recombination, and contains a conserved SWIM domain that is necessary for both [Source:SGD;Acc:S000002485] 0.41183171391451967 82 YHL036W Low affinity methionine permease; similar to Mup1p [Source:SGD;Acc:S000001028] 0.40683413835446464 85 YLL061W High-affinity S-methylmethionine permease; required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p [Source:SGD;Acc:S000003984] 0.40582746635881095 87 YER104W Protein with a role in regulation of Ty1 transposition [Source:SGD;Acc:S000000906] 0.40473078629541215 89 YIL074C 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase; 3PG dehydrogenase that catalyzes the first step in serine and glycine biosynthesis; also functions as an alpha-ketoglutarate reductase, converting alpha-ketoglutarate to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER33 has a paralog, SER3, that arose from the whole genome duplication [Source:SGD;Acc:S000001336] 0.3982527085063577 96 YFL055W Low-affinity amino acid permease; may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000001839] 0.39502307404380804 100