Sequence Description Alias PCC hrr YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex [Source:SGD;Acc:S000002391] 0.6254593900965135 8 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication [Source:SGD;Acc:S000000619] 0.5783128341679131 6 YGL188C-A Putative protein of unknown function [Source:SGD;Acc:S000028635] 0.5688472035353724 3 YML054C-A Putative protein of unknown function [Source:SGD;Acc:S000028573] 0.528669747660864 5 YDR524W-C Putative protein of unknown function; small ORF identified by SAGE; deletion strains are moderately sensitive to the radiomimetic drug bleomycin [Source:SGD;Acc:S000028740] 0.5039888741414118 10 YCL054W-A Short open reading frame, shows evidence of translation; may be new protein-coding gene that originated de novo from noncoding sequence; same allele found in at least 33 other S. cerevisiae strains; at least 3 strains have a second allele with three nucleotide substitutions leading to two amino acid differences [Source:SGD;Acc:S000178054] 0.4866542042691068 11 YBR296C-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028605] 0.48431781884435104 10 YJL127W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007612] 0.472339175692591 9 YKL162C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007244] 0.4656719714690475 13 YPL152W-A Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028721] 0.4575257734311719 18 YDR003W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028819] 0.4572328208383674 29 YMR158C-A Putative protein of unknown function; may contain a lipid attachment site; YMR158C-A is not an essential gene [Source:SGD;Acc:S000007249] 0.43167626621925276 23 YCR095W-A Putative protein of unknown function [Source:SGD;Acc:S000029724] 0.4291201462137142 16 YJL127C-B Putative protein of unknown function; identified based on homology to the filamentous fungus, Ashbya gossypii; SWAT-GFP and seamless-GFP fusion proteins localize to the mitochondria [Source:SGD;Acc:S000028522] 0.4288437731227754 33 YDR510C-A Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028615] 0.41992817508116626 15 YBL100W-C Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028598] 0.41903846379741344 16 YFR012W-A Putative protein of unknown function; identified by homology [Source:SGD;Acc:S000007606] 0.4075104920693796 17 YDL133C-A Ribosomal 60S subunit protein L41B; comprises only 25 amino acids; rpl41a rpl41b double null mutant is viable; homologous to mammalian ribosomal protein L41, no bacterial homolog; RPL41B has a paralog, RPL41A, that arose from the whole genome duplication [Source:SGD;Acc:S000002293] 0.4073185038677729 18 YGL007C-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; deletion exhibits slow-growth phenotype; computationally predicted to have a role in cell budding [Source:SGD;Acc:S000028632] 0.40528671968315233 19 YJL052C-A Putative protein of unknown function; identified based on comparison to related yeast species; mCherry fusion protein localizes to the vacuole [Source:SGD;Acc:S000007610] 0.40437026129856013 20 YMR315W-A Putative protein of unknown function [Source:SGD;Acc:S000028697] 0.4028863791875932 21 YDL184C Ribosomal 60S subunit protein L41A; comprises only 25 amino acids; rpl41a rpl41b double null mutant is viable; homologous to mammalian ribosomal protein L41, no bacterial homolog; RPL41A has a paralog, RPL41B, that arose from the whole genome duplication [Source:SGD;Acc:S000002343] 0.394967922703929 22 YGL006W-A Putative protein of unknown function; identified by SAGE [Source:SGD;Acc:S000028769] 0.39131874191746163 23 YOL038C-A Putative protein of unknown function; identified by SAGE analysis [Source:SGD;Acc:S000028812] 0.3912671735779713 24 YDL159W-A Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species [Source:SGD;Acc:S000007599] 0.3854922669681099 25 YJL077W-B Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028662] 0.38383117749625656 26 YOR161C-C Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028712] 0.38280770287345195 27 YBR196C-B Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028816] 0.38253077832372084 28 YDR524C-A Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028616] 0.3810614598782464 29 YOR045W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005571] 0.37868144194531783 52 YOR314W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007629] 0.3717730475476933 31 YBR209W Putative protein of unknown function; conserved across S. cerevisiae strains; YBR209W is not an essential gene [Source:SGD;Acc:S000000413] 0.3695241322331239 35 YPR133W-A Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore [Source:SGD;Acc:S000006433] 0.36861135747098034 33 YMR013W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the characterized snoRNA gene snR73 [Source:SGD;Acc:S000007622] 0.36819171853659555 34 YML007C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria [Source:SGD;Acc:S000007621] 0.3657340319912241 35 YLR466C-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000028686] 0.3634065361839281 36 YER138W-A Putative protein of unknown function; YER138W-A has a paralog, YBL107W-A, that arose from a single-locus duplication [Source:SGD;Acc:S000007239] 0.3616555521135535 37 YFR010W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized gene YFR011C; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028824] 0.35401930411181753 38 YDR118W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified using a combination of expression profiling and mass spectrometry [Source:SGD;Acc:S000028820] 0.34283434873675056 39 YMR182W-A Putative protein of unknown function [Source:SGD;Acc:S000028693] 0.341694384997754 40 YAR035C-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; predicted to have a role in cell budding based on computational "guilt by association" analysis [Source:SGD;Acc:S000028595] 0.3379345671553294 41 YHR032C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YHR032W-A [Source:SGD;Acc:S000028646] 0.33553073787976223 42 YGR146C-A Putative protein of unknown function [Source:SGD;Acc:S000028638] 0.3289653634593015 52 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain [Source:SGD;Acc:S000002225] 0.32843062895219016 66 YGR122C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; similar to YLR334C and YOL106W [Source:SGD;Acc:S000007240] 0.3274995641420394 45 YER175W-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028625] 0.3264504129196435 46 YDR276C Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential [Source:SGD;Acc:S000002684] 0.3222924186120957 51 YOR008W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007628] 0.32164891031209875 48 YIR018C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028837] 0.3184746117138971 49 YDL061C Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S29 and bacterial S14; RPS29B has a paralog, RPS29A, that arose from the whole genome duplication [Source:SGD;Acc:S000002219] 0.31822418256207063 50 YHL015W-A Putative protein of unknown function [Source:SGD;Acc:S000028828] 0.31601695224789766 51 YMR046W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007248] 0.31191167401717124 52 YMR247W-A Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole [Source:SGD;Acc:S000028849] 0.3014412909596437 53 YDR169C-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028538] 0.29617891225736864 54 YJL205C Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; SWAT-GFP and mCherry fusion proteins localize to the cytosol [Source:SGD;Acc:S000003742] 0.2940846369783716 69 YNL024C-A Essential protein suggested to function early in the secretory pathway; inviability is suppressed by overexpression of Golgi protein Tvp23p; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and cytosol respectively; ortholog of human Kish [Source:SGD;Acc:S000028698] 0.29196062235528747 74 YDR320W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the verified gene DAD4/YDR320C-A [Source:SGD;Acc:S000028821] 0.2915458735459329 57 YHL048C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028829] 0.2903506342805634 59 YMR272W-B Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole [Source:SGD;Acc:S000028696] 0.28969070585089207 60 YNL070W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005014] 0.28885437169699585 61 YJL222W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000028664] 0.2864561733250601 62 YGL041C-B Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum [Source:SGD;Acc:S000028548] 0.28513282790736416 63 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms [Source:SGD;Acc:S000007247] 0.2762980953831414 100 YLR406C-A Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole [Source:SGD;Acc:S000028683] 0.27461965714853753 92 YOR376W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028586] 0.27408488947635157 89 YFR032C-A Ribosomal 60S subunit protein L29; not essential for translation, but required for proper joining of large and small ribosomal subunits and for normal translation rate; homologous to mammalian ribosomal protein L29, no bacterial homolog [Source:SGD;Acc:S000006437] 0.2574889304817996 68 YDR034W-B Predicted tail-anchored plasma membrane protein; contains conserved CYSTM module; related proteins in other organisms may be involved in response to stress; N- and C-terminal fusion proteins localize to the cell periphery; YDR034W-B has a paralog, YBR056W-A, that arose from the whole genome duplication [Source:SGD;Acc:S000007234] 0.24814168155763355 70 YJL047C-A Putative protein of unknown function [Source:SGD;Acc:S000028804] 0.24713886013756076 71 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p; binds to and inhibits GTP-bound Ras2p at the endoplasmic reticulum (ER); component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein [Source:SGD;Acc:S000028423] 0.24519359091271836 81 YKL106C-A Putative protein of unknown function; identified by homology to uncharacterized proteins in other fungi [Source:SGD;Acc:S000007616] 0.24375136069284625 73 YNL145W Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1 [Source:SGD;Acc:S000005089] 0.2393639646356175 74 YOR302W CPA1 uORF; Arginine attenuator peptide, regulates translation of the CPA1 mRNA [Source:SGD;Acc:S000005828] 0.23870290601722036 75 YBR126W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-A; identified by SAGE [Source:SGD;Acc:S000028738] 0.23700153493006293 76 YPR159C-A Protein of unknown function; SWAT-GFP and mCherry fusion proteins localize to the cytosol; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028725] 0.23515868046390856 78 YGR174W-A Putative protein of unknown function; predicted to have a role in cell budding based on computational "guilt by association" analysis [Source:SGD;Acc:S000028639] 0.2321259718682077 79 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; relocalizes to the cytosol in response to hypoxia; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair [Source:SGD;Acc:S000007603] 0.23160678029802612 80 YBL071C-B Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028597] 0.22894054175237138 81 YGR025W Putative protein of unknown function; conserved across S. cerevisiae strains [Source:SGD;Acc:S000003257] 0.22888904610774746 82 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication [Source:SGD;Acc:S000002103] 0.22691668303502935 83 YBL107W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the Ty2 LTR YBLWdelta2; YBL107W-A has a paralog, YER138W-A, that arose from a single-locus duplication [Source:SGD;Acc:S000007229] 0.22580454345859446 85 YBR191W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007594] 0.22146548379367273 86 YLR120W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YLR121C [Source:SGD;Acc:S000028674] 0.217812122595191 87 YHR072W-A Subunit of box H/ACA snoRNP complex; required for pseudouridylation and processing of pre-18S rRNA [Source:SGD;Acc:S000007455] 0.217616154629312 88 YNL130C-A Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose [Source:SGD;Acc:S000028579] 0.21366448292360102 91 YLR402W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000004394] 0.20809278815682983 98 YDR461W Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2 [Source:SGD;Acc:S000002869] 0.20602414652357723 95