Sequence Description Alias PCC hrr YML081C-A Subunit of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms [Source:SGD;Acc:S000007247] 0.6906738066117929 4 YMR256C Subunit VII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain [Source:SGD;Acc:S000004869] 0.5614928337168078 8 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain [Source:SGD;Acc:S000002225] 0.5538749430077741 10 YOR045W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005571] 0.5367775692818627 10 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex [Source:SGD;Acc:S000002391] 0.516398865365526 16 YJL205C Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; SWAT-GFP and mCherry fusion proteins localize to the cytosol [Source:SGD;Acc:S000003742] 0.5069355836799732 14 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex [Source:SGD;Acc:S000003415] 0.49613456498221525 34 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication [Source:SGD;Acc:S000000619] 0.4704073171110136 19 YBL039W-B Putative protein of unknown function; mCherry fusion protein localizes to the vacuole [Source:SGD;Acc:S000028517] 0.4639733862725367 10 YKL162C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007244] 0.4616860076330211 14 YJL127C-B Putative protein of unknown function; identified based on homology to the filamentous fungus, Ashbya gossypii; SWAT-GFP and seamless-GFP fusion proteins localize to the mitochondria [Source:SGD;Acc:S000028522] 0.4516125804322363 25 YMR251W-A Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor; HOR7 has a paralog, DDR2, that arose from the whole genome duplication [Source:SGD;Acc:S000004864] 0.4275089248921752 20 YNL070W Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex [Source:SGD;Acc:S000005014] 0.42508385213757316 14 YPR010C-A Putative protein of unknown function; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the cytosol; conserved among Saccharomyces sensu stricto species [Source:SGD;Acc:S000122558] 0.4200309646924934 73 YDR276C Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential [Source:SGD;Acc:S000002684] 0.41708920313869435 24 YDR003W-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028819] 0.41091417672293085 36 YMR158C-A Putative protein of unknown function; may contain a lipid attachment site; YMR158C-A is not an essential gene [Source:SGD;Acc:S000007249] 0.3826243059244866 42 YML054C-A Putative protein of unknown function [Source:SGD;Acc:S000028573] 0.3786741807669766 49 YDR524W-C Putative protein of unknown function; small ORF identified by SAGE; deletion strains are moderately sensitive to the radiomimetic drug bleomycin [Source:SGD;Acc:S000028740] 0.3767219255874584 28 YBR209W Putative protein of unknown function; conserved across S. cerevisiae strains; YBR209W is not an essential gene [Source:SGD;Acc:S000000413] 0.37611427093820243 31 YBR296C-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028605] 0.3733996035985794 27 YGL188C-A Putative protein of unknown function [Source:SGD;Acc:S000028635] 0.3731707272117205 24 YNL024C-A Essential protein suggested to function early in the secretory pathway; inviability is suppressed by overexpression of Golgi protein Tvp23p; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and cytosol respectively; ortholog of human Kish [Source:SGD;Acc:S000028698] 0.3704711340070234 29 YOL077W-A Subunit k of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase [Source:SGD;Acc:S000007339] 0.3695052569640558 27 YDL133C-A Ribosomal 60S subunit protein L41B; comprises only 25 amino acids; rpl41a rpl41b double null mutant is viable; homologous to mammalian ribosomal protein L41, no bacterial homolog; RPL41B has a paralog, RPL41A, that arose from the whole genome duplication [Source:SGD;Acc:S000002293] 0.3664755211085317 28 YCL054W-A Short open reading frame, shows evidence of translation; may be new protein-coding gene that originated de novo from noncoding sequence; same allele found in at least 33 other S. cerevisiae strains; at least 3 strains have a second allele with three nucleotide substitutions leading to two amino acid differences [Source:SGD;Acc:S000178054] 0.3624433263336121 29 YEL050W-A Dubious open reading frame unlikely to encode a functional protein; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028545] 0.35850034809084713 31 YNL097C-B Putative protein of unknown function [Source:SGD;Acc:S000028699] 0.35401930411181753 38 YDL184C Ribosomal 60S subunit protein L41A; comprises only 25 amino acids; rpl41a rpl41b double null mutant is viable; homologous to mammalian ribosomal protein L41, no bacterial homolog; RPL41A has a paralog, RPL41B, that arose from the whole genome duplication [Source:SGD;Acc:S000002343] 0.34185449219840774 32 YOL038C-A Putative protein of unknown function; identified by SAGE analysis [Source:SGD;Acc:S000028812] 0.33519076906365824 35 YBR230W-A Putative protein of unknown function; YBR230W-A has a paralog, COQ8, that arose from the whole genome duplication [Source:SGD;Acc:S000029722] 0.33135669387450317 35 YOR304C-A Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck [Source:SGD;Acc:S000005830] 0.3294751939821363 66 YML007C-A Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria [Source:SGD;Acc:S000007621] 0.32503867114132146 44 YFL041W-A Putative protein of unknown function; identified by fungal homology and RT-PCR [Source:SGD;Acc:S000028547] 0.3206186630100842 39 YDR119W-A Stabilizes or regulates formation of respiratory chain supercomplexes composed of Complex III (ubiquinol-cytochrome c reductase) and Complex IV (cytochrome c oxidase) [Source:SGD;Acc:S000113555] 0.311105458993746 46 YMR182W-A Putative protein of unknown function [Source:SGD;Acc:S000028693] 0.3095804637022538 43 YDR118W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified using a combination of expression profiling and mass spectrometry [Source:SGD;Acc:S000028820] 0.30764459321063564 45 YJL077W-B Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028662] 0.30743674676789906 55 YBL100W-C Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028598] 0.3023911416981612 55 YMR247W-A Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole [Source:SGD;Acc:S000028849] 0.2978351500232155 50 YJL127W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000007612] 0.29760819273694944 54 YCR095W-A Putative protein of unknown function [Source:SGD;Acc:S000029724] 0.29744539186581853 68 YHR072W-A Subunit of box H/ACA snoRNP complex; required for pseudouridylation and processing of pre-18S rRNA [Source:SGD;Acc:S000007455] 0.29672010911308 53 YLR402W Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data [Source:SGD;Acc:S000004394] 0.28891351472273485 57 YOR182C Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S30, no bacterial homolog; RPS30B has a paralog, RPS30A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005708] 0.2881755265912749 59 YBR126W-B Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-A; identified by SAGE [Source:SGD;Acc:S000028738] 0.2865611737237221 61 YOL052C-A Multi-stress response protein; expression is activated by a variety of xenobiotic agents and environmental or physiological stresses; DDR2 has a paralog, HOR7, that arose from the whole genome duplication [Source:SGD;Acc:S000005413] 0.2783702846853223 87 YGL007C-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; deletion exhibits slow-growth phenotype; computationally predicted to have a role in cell budding [Source:SGD;Acc:S000028632] 0.27795010426737565 66 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p; binds to and inhibits GTP-bound Ras2p at the endoplasmic reticulum (ER); component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein [Source:SGD;Acc:S000028423] 0.2750012200775833 67 YDR034W-B Predicted tail-anchored plasma membrane protein; contains conserved CYSTM module; related proteins in other organisms may be involved in response to stress; N- and C-terminal fusion proteins localize to the cell periphery; YDR034W-B has a paralog, YBR056W-A, that arose from the whole genome duplication [Source:SGD;Acc:S000007234] 0.2749879167681892 68 YHL048C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028829] 0.2701475723773492 70 YHR032C-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YHR032W-A [Source:SGD;Acc:S000028646] 0.26942980932759564 71 YDL061C Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S29 and bacterial S14; RPS29B has a paralog, RPS29A, that arose from the whole genome duplication [Source:SGD;Acc:S000002219] 0.268109858878777 72 YFR035C Putative protein of unknown function; deletion mutant exhibits synthetic phenotype with alpha-synuclein [Source:SGD;Acc:S000001931] 0.2669863064137546 74 YLR287C-A Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S30, no bacterial homolog; RPS30A has a paralog, RPS30B, that arose from the whole genome duplication [Source:SGD;Acc:S000004278] 0.2650985894807148 76 YER053C-A Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000007523] 0.26378190994731965 77 YDR007W Phosphoribosylanthranilate isomerase; catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA); enhances vegetative growth at low and high temperatures when used as an auxotrophic marker in strains such as W303 [Source:SGD;Acc:S000002414] 0.260010257505669 81 YDR008C Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps TRP1/YDR007W on opposite strand [Source:SGD;Acc:S000002415] 0.25845359825044006 82 YMR013W-A Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the characterized snoRNA gene snR73 [Source:SGD;Acc:S000007622] 0.25396681794199355 85 YJR120W Protein of unknown function; essential for growth under anaerobic conditions; mutation causes decreased expression of ATP2, impaired respiration, defective sterol uptake, and altered levels/localization of ABC transporters Aus1p and Pdr11p [Source:SGD;Acc:S000003881] 0.25376034765420463 86 YER175W-A Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028625] 0.252102653558758 88 YKL106C-A Putative protein of unknown function; identified by homology to uncharacterized proteins in other fungi [Source:SGD;Acc:S000007616] 0.24903665385364893 91 YIR018C-A Putative protein of unknown function; identified by expression profiling and mass spectrometry [Source:SGD;Acc:S000028837] 0.24742382804697582 92 YJL052C-A Putative protein of unknown function; identified based on comparison to related yeast species; mCherry fusion protein localizes to the vacuole [Source:SGD;Acc:S000007610] 0.2438126487551826 94 YJL133C-A Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000028805] 0.24055125740464597 96