GO:0003852: 2-isopropylmalate synthase activity (Molecular function)

"Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+)." [EC:2.3.3.13, RHEA:21524]


There are 18 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_7 Saccharomyces cerevisiae 0.84 % 0.001295 0.008218
Cluster_46 Aspergillus nidulans 1.52 % 0.006265 0.016367
Cluster_42 Aspergillus niger 0.88 % 0.008177 0.019269
Cluster_45 Candida albicans 2.22 % 0.014032 0.047552
Cluster_120 Coprinopsis cinerea 1.56 % 0.004792 0.012741
Cluster_37 Fusarium graminearum 0.67 % 0.011267 0.030349
Cluster_50 Neurospora crassa 0.56 % 0.016469 0.048736
Cluster_78 Puccinia striiformis 1.1 % 0.00603 0.020941
Sequences (18) (download table)

InterPro Domains

GO Terms

Family Terms