"sequence_id","alias","species","description","type"
"AFR93119","No alias","Cryptococcus neoformans","high-affinity phosphodiesterase;3'5'-cyclic nucleotide phosphodiesterase","protein_coding"
"AFR93824","No alias","Cryptococcus neoformans","phosphatidylinositol phospholipase C, delta;Phosphatidylinositol-specific phospholipase C, X domain;Phosphatidylinositol-specific phospholipase C, Y domain;C2 domain","protein_coding"
"AFR94346","No alias","Cryptococcus neoformans","phosphodiesterase;cAMP phosphodiesterases class-II","protein_coding"
"AFR94947","No alias","Cryptococcus neoformans","tyrosyl-DNA phosphodiesterase 1;Tyrosyl-DNA phosphodiesterase","protein_coding"
"AFR95196","No alias","Cryptococcus neoformans","hypothetical protein;Cyclic phosphodiesterase-like protein","protein_coding"
"AFR95292","No alias","Cryptococcus neoformans","cyclin-dependent protein kinase inhibitor;SPX domain;Ankyrin repeat;Glycerophosphoryl diester phosphodiesterase family;Ankyrin repeats (3 copies)","protein_coding"
"AFR95900","No alias","Cryptococcus neoformans","glycerophosphodiesterase;Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"AFR97081","No alias","Cryptococcus neoformans","glycerophosphoryl diester phosphodiesterase;Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"AGV14234","No alias","Cryptococcus neoformans","phosphodiesterase;cAMP phosphodiesterases class-II","protein_coding"
"AGV14603","No alias","Cryptococcus neoformans","glycerophosphoryl diester phosphodiesterase;Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"AOA65839","No alias","Komagataella phaffii","Cyclic-AMP phosphodiesterase, class-II","protein_coding"
"AOA66022","No alias","Komagataella phaffii","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"AOA66531","No alias","Komagataella phaffii","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"AOA67096","No alias","Komagataella phaffii","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"AOA68945","No alias","Komagataella phaffii","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"AOA69998","No alias","Komagataella phaffii","Phospholipase C, phosphatidylinositol-specific, Y domain","protein_coding"
"CAG77960","No alias","Yarrowia lipolytica","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"CAG80293","No alias","Yarrowia lipolytica","Cyclic-AMP phosphodiesterase, class-II","protein_coding"
"CAG80305","No alias","Yarrowia lipolytica","Ankyrin repeat-containing domain","protein_coding"
"CAG80726","No alias","Yarrowia lipolytica","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"CAG81728","No alias","Yarrowia lipolytica","C2 domain","protein_coding"
"CAG83547","No alias","Yarrowia lipolytica","SPX domain","protein_coding"
"CAG83786","No alias","Yarrowia lipolytica","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"CAG84217","No alias","Yarrowia lipolytica","2',3'-cyclic-nucleotide 3'-phosphodiesterase","protein_coding"
"CAK36980","No alias","Aspergillus niger","3'5'-cyclic nucleotide phosphodiesterase","protein_coding"
"CAK37348","No alias","Aspergillus niger","cAMP phosphodiesterases class-II","protein_coding"
"CAK42283","No alias","Aspergillus niger","Ubiquitin interaction motif","protein_coding"
"CAK42462","No alias","Aspergillus niger","Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"CAK44459","No alias","Aspergillus niger","Phosphatidylinositol-specific phospholipase C, Y domain","protein_coding"
"CAK45602","No alias","Aspergillus niger","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"CAK47581","No alias","Aspergillus niger","Tyrosyl-DNA phosphodiesterase","protein_coding"
"CAK48701","No alias","Aspergillus niger","Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"CBF70601","No alias","Aspergillus nidulans","tyrosyl-DNA phosphodiesterase, putative","protein_coding"
"CBF71038","No alias","Aspergillus nidulans","conserved hypothetical protein","protein_coding"
"CBF77792","No alias","Aspergillus nidulans","cyclin dependent kinase inhibitor Pho81, putative","protein_coding"
"CBF83693","No alias","Aspergillus nidulans","phospholipase C, putative","protein_coding"
"CBF84110","No alias","Aspergillus nidulans","high affinity cAMP phosphodiesterase, putative","protein_coding"
"CBF88703","No alias","Aspergillus nidulans","cAMP-specific phosphodiesterase, putative","protein_coding"
"CBF89031","No alias","Aspergillus nidulans","Phosphoinositide-specific phospholipase C Fragment","protein_coding"
"CBF89396","No alias","Aspergillus nidulans","glycerophosphoryl diester phosphodiesterase family protein","protein_coding"
"CBF90127","No alias","Aspergillus nidulans","glycerophosphocholine phosphodiesterase Gde1, putative","protein_coding"
"EAA27934","No alias","Neurospora crassa","Ankyrin repeats (many copies)","protein_coding"
"EAA28472","No alias","Neurospora crassa","Cyclic-AMP phosphodiesterase, class-II","protein_coding"
"EAA28731","No alias","Neurospora crassa","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"EAA31508","No alias","Neurospora crassa","C2 domain","protein_coding"
"EAA33143","No alias","Neurospora crassa","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"EAA33837","No alias","Neurospora crassa","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"EAA33860","No alias","Neurospora crassa","C2 domain","protein_coding"
"EAA35009","No alias","Neurospora crassa","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"EAL85605","No alias","Aspergillus fumigatus","conserved hypothetical protein","protein_coding"
"EAL87197","No alias","Aspergillus fumigatus","glycerophosphoryl diester phosphodiesterase family protein","protein_coding"
"EAL88234","No alias","Aspergillus fumigatus","high affinity cAMP phosphodiesterase, putative","protein_coding"
"EAL89065","No alias","Aspergillus fumigatus","glycerophosphoryl diester phosphodiesterase family protein","protein_coding"
"EAL90184","No alias","Aspergillus fumigatus","cyclin dependent kinase inhibitor Pho81, putative","protein_coding"
"EAL90657","No alias","Aspergillus fumigatus","1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase Plc1, putative","protein_coding"
"EAL90820","No alias","Aspergillus fumigatus","cAMP-specific phosphodiesterase, putative","protein_coding"
"EAL91453","No alias","Aspergillus fumigatus","glycerophosphocholine phosphodiesterase Gde1, putative","protein_coding"
"EAL92782","No alias","Aspergillus fumigatus","phosphoinositide-specific phospholipase C, putative","protein_coding"
"EAL93402","No alias","Aspergillus fumigatus","tyrosyl-DNA phosphodiesterase, putative","protein_coding"
"EAU81219","No alias","Coprinopsis cinerea","1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1","protein_coding"
"EAU81283","No alias","Coprinopsis cinerea","phosphoinositide-specific phospholipase C","protein_coding"
"EAU82804","No alias","Coprinopsis cinerea","glycerophosphodiesterase","protein_coding"
"EAU83602","No alias","Coprinopsis cinerea","phospholipase C","protein_coding"
"EAU84324","No alias","Coprinopsis cinerea","cyclin-dependent protein kinase inhibitor","protein_coding"
"EAU84411","No alias","Coprinopsis cinerea","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"EAU87927","No alias","Coprinopsis cinerea","Tyrosyl-DNA phosphodiesterase IUbiquitin interacting motif","protein_coding"
"EAU88411","No alias","Coprinopsis cinerea","class II cAMP phosphodiesterase","protein_coding"
"EAU88707","No alias","Coprinopsis cinerea","2',3'-cyclic-nucleotide 3'-phosphodiesterase","protein_coding"
"EAU89427","No alias","Coprinopsis cinerea","high-affinity phosphodiesterase","protein_coding"
"EAU93188","No alias","Coprinopsis cinerea","glycerophosphoryl diester phosphodiesterase","protein_coding"
"EDN90633","No alias","Sclerotinia sclerotiorum","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"EDN94342","No alias","Sclerotinia sclerotiorum","SPX domain","protein_coding"
"EDN94484","No alias","Sclerotinia sclerotiorum","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"EDN94485","No alias","Sclerotinia sclerotiorum","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"EDN97740","No alias","Sclerotinia sclerotiorum","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"EDN99349","No alias","Sclerotinia sclerotiorum","Ankyrin repeat-containing domain","protein_coding"
"EDO01074","No alias","Sclerotinia sclerotiorum","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"EDO03273","No alias","Sclerotinia sclerotiorum","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"EDO04928","No alias","Sclerotinia sclerotiorum","Cyclic-AMP phosphodiesterase, class-II","protein_coding"
"EDO64907","No alias","Neurospora crassa","Phospholipase C, phosphatidylinositol-specific, Y domain","protein_coding"
"EED49701","No alias","Aspergillus flavus","glycerophosphoryl diester phosphodiesterase family protein","protein_coding"
"EED50525","No alias","Aspergillus flavus","glycerophosphocholine phosphodiesterase Gde1, putative","protein_coding"
"EED50629","No alias","Aspergillus flavus","tyrosyl-DNA phosphodiesterase, putative","protein_coding"
"EED51309","No alias","Aspergillus flavus","tyrosyl-DNA phosphodiesterase, putative","protein_coding"
"EED52962","No alias","Aspergillus flavus","ankyrin repeat-containing protein, putative","protein_coding"
"EED54021","No alias","Aspergillus flavus","cyclin dependent kinase inhibitor Pho81, putative","protein_coding"
"EED54565","No alias","Aspergillus flavus","1-phosphatidylinositol-bisphosphate phosphodiesterase Plc1, putative","protein_coding"
"EED55728","No alias","Aspergillus flavus","high affinity cAMP phosphodiesterase, putative","protein_coding"
"EED57779","No alias","Aspergillus flavus","cAMP-specific phosphodiesterase, putative","protein_coding"
"EED58026","No alias","Aspergillus flavus","phosphoinositide-specific phospholipase C, putative","protein_coding"
"EED81322","No alias","Postia placenta","2',3'-cyclic-nucleotide 3'-phosphodiesterase","protein_coding"
"EED85214","No alias","Postia placenta","2',3'-cyclic-nucleotide 3'-phosphodiesterase","protein_coding"
"EGR46682","No alias","Trichoderma reesei","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"EGR47791","No alias","Trichoderma reesei","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"EGR48455","No alias","Trichoderma reesei","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"EGR48533","No alias","Trichoderma reesei","Cyclic-AMP phosphodiesterase, class-II","protein_coding"
"EGR48686","No alias","Trichoderma reesei","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"EGR48733","No alias","Trichoderma reesei","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"EGR49344","No alias","Trichoderma reesei","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"EGR51416","No alias","Trichoderma reesei","Phospholipase C, phosphatidylinositol-specific, Y domain","protein_coding"
"EGR51638","No alias","Trichoderma reesei","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"EGR52261","No alias","Trichoderma reesei","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"EJF57812","No alias","Dichomitus squalens","3'5'-cyclic nucleotide phosphodiesterase","protein_coding"
"EJF59929","No alias","Dichomitus squalens","C2 domain","protein_coding"
"EJF61296","No alias","Dichomitus squalens","Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"EJF61409","No alias","Dichomitus squalens","Tyrosyl-DNA phosphodiesterase","protein_coding"
"EJF62321","No alias","Dichomitus squalens","Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"EJF62322","No alias","Dichomitus squalens","Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"ESA42188","No alias","Neurospora crassa","2',3'-cyclic-nucleotide 3'-phosphodiesterase","protein_coding"
"ESA42189","No alias","Neurospora crassa","2',3'-cyclic-nucleotide 3'-phosphodiesterase","protein_coding"
"ESA42580","No alias","Neurospora crassa","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"ESA42581","No alias","Neurospora crassa","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"ESA43394","No alias","Neurospora crassa","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"ESA43395","No alias","Neurospora crassa","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"ESU06795","No alias","Fusarium graminearum","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"ESU06869","No alias","Fusarium graminearum","ankyrin repeat protein nuc-2","protein_coding"
"ESU08048","No alias","Fusarium graminearum","Ubiquitin interacting motif","protein_coding"
"ESU09283","No alias","Fusarium graminearum","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"ESU10314","No alias","Fusarium graminearum","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"ESU10968","No alias","Fusarium graminearum","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"ESU11929","No alias","Fusarium graminearum","Phospholipase C, phosphatidylinositol-specific, Y domain","protein_coding"
"ESU12235","No alias","Fusarium graminearum","Tyrosyl-DNA phosphodiesterase I","protein_coding"
"ESU12749","No alias","Fusarium graminearum","Cyclic-AMP phosphodiesterase, class-II","protein_coding"
"ESU12819","No alias","Fusarium graminearum","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"ESU13074","No alias","Fusarium graminearum","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"ESU13759","No alias","Fusarium graminearum","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"ESU14506","No alias","Fusarium graminearum","Phosphatidylinositol-specific phospholipase C, X domain","protein_coding"
"ESU16564","No alias","Fusarium graminearum","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"KHC70523","No alias","Candida albicans","2',3'-cyclic-nucleotide 3'-phosphodiesterase;Cyclic phosphodiesterase-like protein","protein_coding"
"KHC72042","No alias","Candida albicans","phosphatidylinositol phospholipase C, delta;"Phosphatidylinositol-specific phospholipase C, Y domain";"Phosphatidylinositol-specific phospholipase C, X domain"","protein_coding"
"KHC73380","No alias","Candida albicans","glycerophosphoryl diester phosphodiesterase;Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"KHC75129","No alias","Candida albicans","3',5'-cyclic-nucleotide phosphodiesterase;cAMP phosphodiesterases class-II","protein_coding"
"KHC75343","No alias","Candida albicans","hypothetical protein;Ankyrin repeats (3 copies);SPX domain;Glycerophosphoryl diester phosphodiesterase family","protein_coding"
"KHC83065","No alias","Candida albicans","3',5'-cyclic-nucleotide phosphodiesterase;3'5'-cyclic nucleotide phosphodiesterase","protein_coding"
"MGG_00211T0","No alias","Pyricularia oryzae","1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 [Source:UniProtKB/TrEMBL;Acc:G4NDT3]","protein_coding"
"MGG_02444T0","No alias","Pyricularia oryzae","Phosphoinositide-specific phospholipase C [Source:UniProtKB/TrEMBL;Acc:G4MRV2]","protein_coding"
"MGG_02514T0","No alias","Pyricularia oryzae","Ankyrin repeat protein nuc-2 [Source:UniProtKB/TrEMBL;Acc:G4MKB9]","protein_coding"
"MGG_04109T0","No alias","Pyricularia oryzae","Putative uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:G4NIU9]","protein_coding"
"MGG_05332T0","No alias","Pyricularia oryzae","1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 [Source:UniProtKB/TrEMBL;Acc:G4N054]","protein_coding"
"MGG_05664T0","No alias","Pyricularia oryzae","cAMP-specific 3',5'-cyclic phosphodiesterase 7B [Source:UniProtKB/TrEMBL;Acc:G4MP01]","protein_coding"
"MGG_06176T0","No alias","Pyricularia oryzae","Putative uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:G4N013]","protein_coding"
"MGG_06704T0","No alias","Pyricularia oryzae","Glycerophosphodiesterase GDE1 [Source:UniProtKB/TrEMBL;Acc:G4ML67]","protein_coding"
"MGG_07707T0","No alias","Pyricularia oryzae","Putative uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:G4N068]","protein_coding"
"MGG_08047T0","No alias","Pyricularia oryzae","Glycerophosphoryl diester phosphodiesterase [Source:UniProtKB/TrEMBL;Acc:G4MXQ5]","protein_coding"
"MGG_08315T0","No alias","Pyricularia oryzae","1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 [Source:UniProtKB/TrEMBL;Acc:G4MWU9]","protein_coding"
"MGG_08847T0","No alias","Pyricularia oryzae","Tyrosyl-DNA phosphodiesterase domain-containing protein [Source:UniProtKB/TrEMBL;Acc:G4MV45]","protein_coding"
"MGG_15018T0","No alias","Pyricularia oryzae","1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1 [Source:UniProtKB/TrEMBL;Acc:G4NJD0]","protein_coding"
"POV98028","No alias","Puccinia striiformis","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"POV98458","No alias","Puccinia striiformis","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"POV98464","No alias","Puccinia striiformis","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"POW00909","No alias","Puccinia striiformis","Ankyrin repeat-containing domain;Ankyrin repeat-containing domain;Glycerophosphodiester phosphodiesterase domain;SPX domain","protein_coding"
"POW01589","No alias","Puccinia striiformis","3'5'-cyclic nucleotide phosphodiesterase, catalytic domain","protein_coding"
"POW09451","No alias","Puccinia striiformis","Glycerophosphodiester phosphodiesterase domain;SPX domain;SPX domain;Ankyrin repeat-containing domain","protein_coding"
"POW12279","No alias","Puccinia striiformis","Glycerophosphodiester phosphodiesterase domain","protein_coding"
"POW14655","No alias","Puccinia striiformis","Phosphatidylinositol-specific phospholipase C, X domain;C2 domain;Phosphoinositide-specific phospholipase C, EF-hand-like domain;Phospholipase C, phosphatidylinositol-specific, Y domain","protein_coding"
"POW16103","No alias","Puccinia striiformis","2',3'-cyclic-nucleotide 3'-phosphodiesterase","protein_coding"
"SPAC22F8.11.1","No alias","Schizosaccharomyces pombe","phosphoinositide phospholipase C Plc1 [Source:PomBase;Acc:SPAC22F8.11]","protein_coding"
"SPAC4D7.02c.1","No alias","Schizosaccharomyces pombe","phosphatidylglycerol phospholipase C Pgc1 (predicted) [Source:PomBase;Acc:SPAC4D7.02c]","protein_coding"
"SPACUNK4.15.1","No alias","Schizosaccharomyces pombe","2',3'-cyclic-nucleotide 3'-phosphodiesterase (predicted) [Source:PomBase;Acc:SPACUNK4.15]","protein_coding"
"SPAPB1E7.05.1","No alias","Schizosaccharomyces pombe","glycerophosphoryl diester phosphodiesterase Gde1 (predicted) [Source:PomBase;Acc:SPAPB1E7.05]","protein_coding"
"SPCC285.09c.1","No alias","Schizosaccharomyces pombe","cAMP-specific phosphodiesterase Cgs2 [Source:PomBase;Acc:SPCC285.09c]","protein_coding"
"SPCP31B10.05.1","No alias","Schizosaccharomyces pombe","tyrosyl-DNA phosphodiesterase Tdp1 [Source:PomBase;Acc:SPCP31B10.05]","protein_coding"
"YBR223C","No alias","Saccharomyces cerevisiae","Tyrosyl-DNA phosphodiesterase I; hydrolyzes 3' and 5'-phosphotyrosyl bonds; involved in the repair of DNA lesions created by topo I and topo II; mutations in the human homolog, TDP1, result in the a neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy (SCAN1); yeast cells and human rhabdomyosarcoma lines that overexpress TDP1 both exhibit elevated dosage chromosomal instability (dCIN) [Source:SGD;Acc:S000000427]","protein_coding"
"YGL248W","No alias","Saccharomyces cerevisiae","Low-affinity cyclic AMP phosphodiesterase; controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation [Source:SGD;Acc:S000003217]","protein_coding"
"YGR247W","No alias","Saccharomyces cerevisiae","Cyclic nucleotide phosphodiesterase; hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003479]","protein_coding"
"YOR360C","No alias","Saccharomyces cerevisiae","High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887]","protein_coding"
"YPL110C","No alias","Saccharomyces cerevisiae","Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes [Source:SGD;Acc:S000006031]","protein_coding"
"YPL206C","No alias","Saccharomyces cerevisiae","Phosphatidylglycerol phospholipase C; regulates phosphatidylglycerol (PG) accumulation via a phospholipase C-type degradation mechanism; PG levels affect mitochondrial function; contains glycerophosphodiester phosphodiesterase motifs [Source:SGD;Acc:S000006127]","protein_coding"
"YPL268W","No alias","Saccharomyces cerevisiae","Phospholipase C; hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes; Plc1p and inositol polyphosphates are required for acetyl-CoA homeostasis which regulates global histone acetylation [Source:SGD;Acc:S000006189]","protein_coding"